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- W4386945185 abstract "This study aimed to determine the comparability of tumor-uptake indices of 18F-FDG in positron emission tomography/computed tomography (PET/CT) and positron emission tomography/magnetic resonance imaging (PET/MRI). 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) PET/CT and PET/MRI were performed on 55 patients with confirmed primary malignancies. PET/CT preceded PET/MRI in all examinations. Accumulation of 18F-FDG in lesions and normal organs (brain, liver) was measured. Maximum and peak standardized uptake values (SUVs; SUVmax and SUVpeak, respectively), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) with margin thresholds of SUV of 50% (MTV50%; TLG50%, respectively) were measured as indices for comparison of measurements in tumors. Comparative indices with tumor SUVmax and liver ratio (TLRmax), brain ratio (TBRmax) were calculated. These indices were compared between PET/CT and PET/MRI examinations. The data measured using PET/CT and PET/MRI showed significant correlations for all tumor indices. The correlation was strongest for SUVpeak (r = 0.933), followed by TBRmax (r = 0.929); and the index ratio of (PET/CT)/(PET/MRI) data was close to 1.0 for TLRmax (1.00 ± 0.22) and TBRmax (1.01 ± 0.21), followed by MTV50% (0.82 ± 0.33) and TLG50% (1.18 ± 0.45). The values of all indices showed strong correlations between PET/CT and PET/MRI examinations. Among them, TLRmax, TBRmax, MTV50%, and TLG50% showed a close value and may be useful for comparison of tumor evaluation between two PET systems." @default.
- W4386945185 created "2023-09-23" @default.
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- W4386945185 date "2023-01-01" @default.
- W4386945185 modified "2023-09-29" @default.
- W4386945185 title "Investigation of tumor assessment between two PET systems using various indices: comparison between PET/CT and PET/MRI systems." @default.
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