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• W4386945893 endingPage "188990" @default.
• W4386945893 startingPage "188990" @default.
• W4386945893 abstract "Treatment resistance, together with acute and late adverse effects, represents critical issues in the management of cancer patients. Promising results from preclinical and clinical research underline the emerging trend of a microbiome-based approach in oncology. Favorable bacterial species and higher gut diversity are associated with increased treatment efficacy, mainly in chemo- and immunotherapy. On the other hand, alterations in the composition and activity of gut microbial communities are linked to intestinal dysbiosis and contribute to high treatment-induced toxicity. In this Review, we provide an overview of studies concerning gut microbiota modulation in patients with solid and hematologic malignancies with a focus on probiotics, prebiotics, postbiotics, and fecal microbiota transplantation. Targeting the gut microbiome might bring clinical benefits and improve patient outcomes. However, a deeper understanding of mechanisms and large clinical trials concerning microbiome and immunological profiling is warranted to identify safe and effective ways to incorporate microbiota-based interventions in routine clinical practice." @default.
• W4386945893 created "2023-09-23" @default.
• W4386945893 creator A5013946712 @default.
• W4386945893 creator A5050740286 @default.
• W4386945893 creator A5052989773 @default.
• W4386945893 creator A5085950307 @default.
• W4386945893 date "2023-11-01" @default.
• W4386945893 modified "2023-09-30" @default.
• W4386945893 title "Modulating the gut microbiota by probiotics, prebiotics, postbiotics, and fecal microbiota transplantation: An emerging trend in cancer patient care" @default.
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