FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386949026> ?p ?o ?g. }

• W4386949026 endingPage "45894" @default.
• W4386949026 startingPage "45886" @default.
• W4386949026 abstract "Coordinating microbial consortia to realize complex synthetic pathways is an area of great interest in the rapidly growing field of biomanufacturing. This work presents a programmable method for assembling living cells based on the surface display of affinity groups, enabling whole-cell catalysis with optimized catalytic efficiency through the rational arrangement of cell assemblies and enzymes. In the context of d-phenyllactic acid (d-PLA) synthesis, four enzymes were rationally arranged considering substrate channeling and protein expression levels. The production efficiencies of d-PLA catalyzed by engineered microbial consortia were 1.31- and 2.55-fold higher than those of biofilm and whole-cell catalysts, respectively. Notably, substrate channeling was identified between the coimmobilized rate-limiting enzymes, resulting in a 3.67-fold improvement in catalytic efficiency compared with hybrid catalysts (free enzymes coupled with whole-cell catalysts). The highest yield of d-PLA catalyzed by microbial consortia was 102.85 ± 3.39 mM with 140 mM benzaldehyde as the substrate. This study proposes a novel approach to cell enzyme assembly for coordinating microbial consortia in multiple enzymatic biosynthesis processes." @default.
• W4386949026 created "2023-09-23" @default.
• W4386949026 creator A5013736647 @default.
• W4386949026 creator A5015145411 @default.
• W4386949026 creator A5021634082 @default.
• W4386949026 creator A5056150603 @default.
• W4386949026 creator A5077083002 @default.
• W4386949026 creator A5087099599 @default.
• W4386949026 date "2023-09-22" @default.
• W4386949026 modified "2023-10-06" @default.
• W4386949026 title "Engineered <i>Escherichia coli</i> Consortia Function in a Programmable Pattern for Multiple Enzymatic Biosynthesis" @default.
• W4386949026 cites W1969089930 @default.
• W4386949026 cites W2021785060 @default.
• W4386949026 cites W2036156669 @default.
• W4386949026 cites W2083686394 @default.
• W4386949026 cites W2111198605 @default.
• W4386949026 cites W2134711862 @default.
• W4386949026 cites W2303875806 @default.
• W4386949026 cites W2319075188 @default.
• W4386949026 cites W2566462605 @default.
• W4386949026 cites W2566722304 @default.
• W4386949026 cites W2726044637 @default.
• W4386949026 cites W2738129447 @default.
• W4386949026 cites W2741483217 @default.
• W4386949026 cites W2785055296 @default.
• W4386949026 cites W2852019624 @default.
• W4386949026 cites W2889373606 @default.
• W4386949026 cites W2891143935 @default.
• W4386949026 cites W2949845517 @default.
• W4386949026 cites W2954536068 @default.
• W4386949026 cites W2989326857 @default.
• W4386949026 cites W2989585088 @default.
• W4386949026 cites W3004889931 @default.
• W4386949026 cites W3009181090 @default.
• W4386949026 cites W3035847987 @default.
• W4386949026 cites W3048444000 @default.
• W4386949026 cites W3092106937 @default.
• W4386949026 cites W3110777803 @default.
• W4386949026 cites W3111671147 @default.
• W4386949026 cites W3114776521 @default.
• W4386949026 cites W3121487663 @default.
• W4386949026 cites W3130132846 @default.
• W4386949026 cites W3160173019 @default.
• W4386949026 cites W3196661147 @default.
• W4386949026 cites W3201451004 @default.
• W4386949026 cites W4214496170 @default.
• W4386949026 cites W4280538549 @default.
• W4386949026 cites W4283218195 @default.
• W4386949026 cites W4361276912 @default.
• W4386949026 doi "https://doi.org/10.1021/acsami.3c09123" @default.
• W4386949026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37738613" @default.
• W4386949026 hasPublicationYear "2023" @default.
• W4386949026 type Work @default.
• W4386949026 citedByCount "0" @default.
• W4386949026 crossrefType "journal-article" @default.
• W4386949026 hasAuthorship W4386949026A5013736647 @default.
• W4386949026 hasAuthorship W4386949026A5015145411 @default.
• W4386949026 hasAuthorship W4386949026A5021634082 @default.
• W4386949026 hasAuthorship W4386949026A5056150603 @default.
• W4386949026 hasAuthorship W4386949026A5077083002 @default.
• W4386949026 hasAuthorship W4386949026A5087099599 @default.
• W4386949026 hasConcept C104317684 @default.
• W4386949026 hasConcept C134121241 @default.
• W4386949026 hasConcept C150903083 @default.
• W4386949026 hasConcept C151730666 @default.
• W4386949026 hasConcept C161790260 @default.
• W4386949026 hasConcept C181199279 @default.
• W4386949026 hasConcept C185592680 @default.
• W4386949026 hasConcept C18903297 @default.
• W4386949026 hasConcept C191897082 @default.
• W4386949026 hasConcept C191908910 @default.
• W4386949026 hasConcept C192562407 @default.
• W4386949026 hasConcept C21951064 @default.
• W4386949026 hasConcept C2775893736 @default.
• W4386949026 hasConcept C2777289219 @default.
• W4386949026 hasConcept C2779343474 @default.
• W4386949026 hasConcept C547475151 @default.
• W4386949026 hasConcept C553450214 @default.
• W4386949026 hasConcept C55493867 @default.
• W4386949026 hasConcept C60644358 @default.
• W4386949026 hasConcept C69118441 @default.
• W4386949026 hasConcept C86803240 @default.
• W4386949026 hasConceptScore W4386949026C104317684 @default.
• W4386949026 hasConceptScore W4386949026C134121241 @default.
• W4386949026 hasConceptScore W4386949026C150903083 @default.
• W4386949026 hasConceptScore W4386949026C151730666 @default.
• W4386949026 hasConceptScore W4386949026C161790260 @default.
• W4386949026 hasConceptScore W4386949026C181199279 @default.
• W4386949026 hasConceptScore W4386949026C185592680 @default.
• W4386949026 hasConceptScore W4386949026C18903297 @default.
• W4386949026 hasConceptScore W4386949026C191897082 @default.
• W4386949026 hasConceptScore W4386949026C191908910 @default.
• W4386949026 hasConceptScore W4386949026C192562407 @default.
• W4386949026 hasConceptScore W4386949026C21951064 @default.
• W4386949026 hasConceptScore W4386949026C2775893736 @default.
• W4386949026 hasConceptScore W4386949026C2777289219 @default.
• W4386949026 hasConceptScore W4386949026C2779343474 @default.
• W4386949026 hasConceptScore W4386949026C547475151 @default.

• next