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- W4386972568 abstract "AntibioticsAntibiotics inhibit the growth or reproduction of microbes, enabling immune system and other defense mechanisms to finish their task. Common mechanisms for operation include acting as a membrane disrupting drug, impeding protein production, DNADeoxyribonucleic acid (DNA) formation, RNA synthesizing, and bacterial cell production overall. AntibioticAntibiotics usage has resulted in multidrug-resistantMultidrug-Resistant (MDR) (MDR) strains of several microbial species linked to human illness outbreaks. For instance, multidrug-resistantMultidrug-Resistant (MDR) Mycobacterium tuberculosis (MDR-TB) has emerged as a prominent disease in both establishing and established countries. Nosocomial sickness (infections contracted while in hospital) can also be quite dangerous. These encompass infections caused by bacteria like Acinetobacter baumannii, Burkholderia cepacia, Campylobacter jejuni, Citrobacter freundii, Clostridium difficile, Enterobacter spp., Enterococcus faecium, Enterococcus faecalis, Escherichia “superbugs” are microorganisms that cause more severe illnesses and deaths than normal because they have acquired mutations that make them resistant to antibioticAntibiotics classes most commonly used to treat them. Certain ß-lactam antibacterials are derived from fungi and kill bacteria by blocking the enzyme transpeptidaseTranspeptidase. Inhibition of topoisomerase II (DNADeoxyribonucleic acid (DNA) gyrase) and topoisomerase IV, quinolones prevent bacteria from producing new DNADeoxyribonucleic acid (DNA). Sulfonamides are structurally similar to the bacterial DHFDihydro Folate (DHF) precursor p-aminobenzoic acid (PABA)P-aminobenzoic Acid (PABA). By acting as fierce inhibitors of PABAP-aminobenzoic Acid (PABA) consumption, sulfonamides reduce DHFDihydro Folate (DHF) production. AntibioticAntibiotics usage has several positive effects, including increased milk production from healthier cows, decreased rates of illness, morbidity, and death, reduced pathogen loads, and more milk of a higher quality and quantity. However, there are concerns that antibioticsAntibiotics used in agriculture may contribute to the rise of bacteria resistant to antimicrobial drugs, which might have an effect on the treatment of illnesses that affect humans. AntibioticAntibiotics residues are also more common in milk produced by cows who have been treated for mastitisMastitis. Bacteria employ four main methods for combating antibioticsAntibiotics: (1) reducing the amount of medicine taken in; (2) altering the drug’s target; (3) rendering the drug ineffective; and (4) engaging in active drug efflux." @default.
- W4386972568 created "2023-09-23" @default.
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- W4386972568 date "2023-01-01" @default.
- W4386972568 modified "2023-09-29" @default.
- W4386972568 title "Antibiotic Drug Resistance" @default.
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- W4386972568 doi "https://doi.org/10.1007/978-3-031-39947-3_5" @default.
- W4386972568 hasPublicationYear "2023" @default.
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