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- W4386972684 abstract "NanofabricationNanofabrication involves the systematic framework of individual elements or molecules of inorganic or organic substances. Micelles were the first polymeric nanoparticlesPolymeric nanoparticles (PNPs) to be created by polymerization techniques. Multiple techniques developed for synthesizing polymeric nanoparticlesPolymeric nanoparticles (PNPs), each tailored to specific needs of particular application or set of physicochemicalPhysicochemical properties of a specific drug. The process of mechanically compressing bulk substances employing template unless original size is greater than nanovalue. Top-down approaches include milling, laser ablation, etching, sputtering, and electroexplosion. The first approach devised for polymericPolymeric NPs from preformed polymerPolymers was solvent evaporation where a polar organic solvent serves to dissolve polymerPolymers and add then active component are dispersed. Emulsification-solvent evaporation is employed for polymericPolymeric NPs fabrication with dimensions of approximately 100 nm, also to acquire nanospheresNanospheres or nanocapsules. Active principles dissolved or dispersed in a polymericPolymeric solution to create nanospheresNanospheres, while drugs dissolved in oil followed by emulsified in an organic polymericPolymeric solution to create nanocapsules, which are then dispersed in an external phase. This method operates on the basis of polymerPolymers interfacial deposition upon transit of organic solvent passes from lipophilic to aqueous phase. NanoparticlesNanoparticles can be physically labeled with a tag like a dye, magnetic particle, or radioactive marker. Numerous imaging approaches, notably fluorescence microscopy, magnetic resonance imaging (MRIMagnetic Resonance Imaging (MRI)), and positron emission tomography (PETPositron Emission Tomography (PET)), can detect a physical identification. Methods for chemically labeling nanoparticlesNanoparticles involve the attachment to particular functional groups that can react with target molecules or receptors such as to target particular receptors on cancer cells, scientists have coupled polymeric nanoparticlesPolymeric nanoparticles (PNPs) with ligands including folate, transferrin, or epidermal growth factor. Using diverse techniques, such as avidin–biotin, streptavidin–biotin, and covalent bonding, researchers have functionalized polymeric nanoparticlesPolymeric nanoparticles (PNPs) with antibodies that target specific cancer cells, such as breast cancer or melanoma cells." @default.
- W4386972684 created "2023-09-23" @default.
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- W4386972684 date "2023-01-01" @default.
- W4386972684 modified "2023-09-29" @default.
- W4386972684 title "Fabrication of Polymeric Nanomaterials" @default.
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- W4386972684 doi "https://doi.org/10.1007/978-3-031-39947-3_2" @default.
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