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- W4386987249 endingPage "112444" @default.
- W4386987249 startingPage "112444" @default.
- W4386987249 abstract "Addressing the need for effective cancer chemotherapy with low adverse effects has been partially possible through innovative therapeutic approaches combining chemotherapeutics with small interfering RNAs (siRNAs) as powerful tools providing unique opportunities to precisely target the oncogenes related to chemoresistance or limited therapeutic response. Curcumin (Cur), a promising anticancer phytochemical, in combination with specific siRNAs, has shown significant success in treating various preclinical cancer models by promoting cell death patterns and hindering tumor metastasis. Further, designing novel carriers for codelivery of Cur and siRNAs increased the effectiveness and safety of treatment due to the enhanced pharmacokinetics of payloads and targeted drug delivery function. Here, we delineated the existing data and recent advancements in Cur and siRNAs cancer combination therapy to promote the current understanding required for future examinations." @default.
- W4386987249 created "2023-09-24" @default.
- W4386987249 creator A5042169973 @default.
- W4386987249 creator A5045032651 @default.
- W4386987249 creator A5052424595 @default.
- W4386987249 creator A5065941540 @default.
- W4386987249 date "2023-10-01" @default.
- W4386987249 modified "2023-09-27" @default.
- W4386987249 title "Recent advances in codelivery of curcumin and siRNA as anticancer therapeutics" @default.
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