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• W4386989145 abstract "Coronavirus disease 2019 (COVID-19) is a contagious infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has caused worldwide transmission. The aim of this systematic review and meta-analysis was to investigate the morbidity and characteristics of seizures after SARS-CoV-2 infection in underage (≤18 y) and to provide valuable reference material for subsequent clinical treatment. PubMed/MEDLINE, Cochrane, and EMBASE databases were searched up to 10th May 2023. We utilized the search strategy of medical subject headings combined with entry terms to search all related literatures. The meta-analysis was performed according to PRISMA reporting guidelines. Risk of bias was assessed using the Newcastle-Ottawa Scale (NOS) and the Agency for Healthcare Research and Quality (AHRQ). A total of 12 articles were selected, including 4153 subjects and 333 seizure-prone minor patients with COVID-19. The morbidity of seizures after SARS-CoV-2 infection in immature patients was approximately 8.2 (95% CI, 4.7%-12.4%). By subgroup analysis, we know that the morbidity of male, Americas, with fever and first occurrence of seizures were 4.2% (95% CI, 0.4-10.5%), 4.6% (95% CI, 0.4%-11.7%), 5.4% (95% CI, 2.6%-9.1%) and 3.7% (95% CI, 0.7%-8.2%), respectively. Generalized seizures are the main type of seizures (80.6%). Seizures can be caused by SARS-CoV-2 infection in underage groups, with a pooled morbidity of 8.2% and a higher morbidity in females, in African regions, in febrile groups and during 2022-2023. In addition, generalized seizures being the predominant seizure type." @default.
• W4386989145 created "2023-09-24" @default.
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• W4386989145 date "2023-11-01" @default.
• W4386989145 modified "2023-10-08" @default.
• W4386989145 title "Association of seizures with COVID-19 infection in underage during the pandemic: a systematic review and meta-analysis" @default.
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• W4386989145 doi "https://doi.org/10.1016/j.eplepsyres.2023.107223" @default.
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