FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386994046> ?p ?o ?g. }

• W4386994046 endingPage "102246" @default.
• W4386994046 startingPage "102246" @default.
• W4386994046 abstract "Pneumonitis is a common complication for patients with locally advanced non-small cell lung cancer undergoing definitive chemoradiotherapy (CRT). It remains unclear whether there is ethnic difference in the incidence of post-CRT pneumonitis.PubMed, Embase, Cochrane Library, and Web of Science were searched for eligible studies from January 1, 2000 to April 30, 2023. The outcomes of interest were incidence rates of pneumonitis. The random-effect model was used for statistical analysis. This meta-analysis was registered with PROSPERO (CRD42023416490).A total of 248 studies involving 28,267 patients were included. Among studies of CRT without immunotherapy, the pooled rates of pneumonitis for Asian patients were significantly higher than that for non-Asian patients (all grade: 66.8%, 95% CI: 59.2%-73.9% vs. 28.1%, 95% CI: 20.4%-36.4%; P < 0.0001; grade ≥2: 25.1%, 95% CI: 22.9%-27.3% vs. 14.9%, 95% CI: 12.0%-18.0%; P < 0.0001; grade ≥3: 6.5%, 95% CI: 5.6%-7.3% vs. 4.6%, 95% CI: 3.4%-5.9%; P = 0.015; grade 5: 0.6%, 95% CI: 0.3%-0.9% vs. 0.1%, 95% CI: 0.0%-0.2%; P < 0.0001). Regarding studies of CRT plus immunotherapy, Asian patients had higher rates of all-grade (74.8%, 95% CI: 63.7%-84.5% vs. 34.3%, 95% CI: 28.7%-40.2%; P < 0.0001) and grade ≥2 (34.0%, 95% CI: 30.7%-37.3% vs. 24.6%, 95% CI: 19.9%-29.3%; P = 0.001) pneumonitis than non-Asian patients, but with no significant differences in the rates of grade ≥3 and grade 5 pneumonitis. Results from subgroup analyses were generally similar to that from the all studies. In addition, the pooled median/mean of lung volume receiving ≥20 Gy and mean lung dose were relatively low in Asian studies compared to that in non-Asian studies.Asian patients are likely to have a higher incidence of pneumonitis than non-Asian patients, which appears to be due to the poor tolerance of lung to radiation. Nevertheless, these findings are based on observational studies and with significant heterogeneity, and need to be validated in future large prospective studies focusing on the subject.None." @default.
• W4386994046 created "2023-09-25" @default.
• W4386994046 creator A5005744006 @default.
• W4386994046 creator A5015065405 @default.
• W4386994046 creator A5017557616 @default.
• W4386994046 creator A5029800010 @default.
• W4386994046 creator A5050733072 @default.
• W4386994046 creator A5055328507 @default.
• W4386994046 creator A5059283157 @default.
• W4386994046 creator A5066706942 @default.
• W4386994046 creator A5076863688 @default.
• W4386994046 creator A5082857859 @default.
• W4386994046 creator A5090462661 @default.
• W4386994046 date "2023-10-01" @default.
• W4386994046 modified "2023-10-17" @default.
• W4386994046 title "Comparison of post-chemoradiotherapy pneumonitis between Asian and non-Asian patients with locally advanced non-small cell lung cancer: a systematic review and meta-analysis" @default.
• W4386994046 cites W1536966791 @default.
• W4386994046 cites W1603299202 @default.
• W4386994046 cites W1645880751 @default.
• W4386994046 cites W166534687 @default.
• W4386994046 cites W1796169359 @default.
• W4386994046 cites W1860436001 @default.
• W4386994046 cites W1930920471 @default.
• W4386994046 cites W1962644888 @default.
• W4386994046 cites W1964634189 @default.
• W4386994046 cites W1965825980 @default.
• W4386994046 cites W1968899146 @default.
• W4386994046 cites W1971384850 @default.
• W4386994046 cites W1971564125 @default.
• W4386994046 cites W1974859918 @default.
• W4386994046 cites W1976520999 @default.
• W4386994046 cites W1979423827 @default.
• W4386994046 cites W1980499639 @default.
• W4386994046 cites W1981128610 @default.
• W4386994046 cites W1983276333 @default.
• W4386994046 cites W1990353764 @default.
• W4386994046 cites W1990665681 @default.
• W4386994046 cites W1995938755 @default.
• W4386994046 cites W1998441291 @default.
• W4386994046 cites W1999058098 @default.
• W4386994046 cites W2003863001 @default.
• W4386994046 cites W2004921695 @default.
• W4386994046 cites W2006981590 @default.
• W4386994046 cites W2009771902 @default.
• W4386994046 cites W2010322092 @default.
• W4386994046 cites W2017044005 @default.
• W4386994046 cites W2017706312 @default.
• W4386994046 cites W2019626224 @default.
• W4386994046 cites W2020180938 @default.
• W4386994046 cites W2027337431 @default.
• W4386994046 cites W2030816399 @default.
• W4386994046 cites W2030901059 @default.
• W4386994046 cites W2032319411 @default.
• W4386994046 cites W2033738330 @default.
• W4386994046 cites W2033794130 @default.
• W4386994046 cites W2035362501 @default.
• W4386994046 cites W2035412694 @default.
• W4386994046 cites W2039738208 @default.
• W4386994046 cites W2040478900 @default.
• W4386994046 cites W2044307910 @default.
• W4386994046 cites W2046261571 @default.
• W4386994046 cites W2048247522 @default.
• W4386994046 cites W2051534601 @default.
• W4386994046 cites W2058951740 @default.
• W4386994046 cites W2062581935 @default.
• W4386994046 cites W2064947884 @default.
• W4386994046 cites W2066336406 @default.
• W4386994046 cites W2068556897 @default.
• W4386994046 cites W2073882297 @default.
• W4386994046 cites W2073953160 @default.
• W4386994046 cites W2074304215 @default.
• W4386994046 cites W2077123624 @default.
• W4386994046 cites W2078206491 @default.
• W4386994046 cites W2086237017 @default.
• W4386994046 cites W2090045542 @default.
• W4386994046 cites W2090406314 @default.
• W4386994046 cites W2093760924 @default.
• W4386994046 cites W2097873964 @default.
• W4386994046 cites W2100348312 @default.
• W4386994046 cites W2100550769 @default.
• W4386994046 cites W2105037851 @default.
• W4386994046 cites W2105603808 @default.
• W4386994046 cites W2107273283 @default.
• W4386994046 cites W2110248134 @default.
• W4386994046 cites W2111834728 @default.
• W4386994046 cites W2121138562 @default.
• W4386994046 cites W2126788016 @default.
• W4386994046 cites W2127264417 @default.
• W4386994046 cites W2133184162 @default.
• W4386994046 cites W2134417792 @default.
• W4386994046 cites W2137425540 @default.
• W4386994046 cites W2140469315 @default.
• W4386994046 cites W2144511316 @default.
• W4386994046 cites W2150032829 @default.
• W4386994046 cites W2154936148 @default.
• W4386994046 cites W2155422011 @default.
• W4386994046 cites W2162595871 @default.
• W4386994046 cites W2165897930 @default.

• next