FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387001872> ?p ?o ?g. }

• W4387001872 abstract "Limited access to specialized palliative care exposes persons with late-stage Alzheimer's disease and related dementias (ADRD) to burdensome treatment and unnecessary hospitalization and their caregivers to avoidable strain and financial burden. Addressing this unmet need, the purpose of this study was to conduct a randomized clinical trial (RCT) of the ADRD-Palliative Care (ADRD-PC) program.The study will use a multisite, RCT design and will be set in five geographically diverse US hospitals. Lead investigators and outcome assessors will be masked. The study will use 1:1 randomization of patient-caregiver dyads, and sites will enroll N = 424 dyads of hospitalized patients with late-stage ADRD with their family caregivers. Intervention dyads will receive the ADRD-PC program of (1) dementia-specific palliative care, (2) standardized caregiver education, and (3) transitional care. Control dyads will receive publicly available educational material on dementia caregiving. Outcomes will be measured at 30 days (interim) and 60 days post-discharge. The primary outcome will be 60-day hospital transfers, defined as visits to an emergency department or hospitalization ascertained from health record reviews and caregiver interviews (aim 1). Secondary patient-centered outcomes, ascertained from 30- and 60-day health record reviews and caregiver telephone interviews, will be symptom treatment, symptom control, use of community palliative care or hospice, and new nursing home transitions (aim 2). Secondary caregiver-centered outcomes will be communication about prognosis and goals of care, shared decision-making about hospitalization and other treatments, and caregiver distress (aim 3). Analyses will use intention-to-treat, and pre-specified exploratory analyses will examine the effects of sex as a biologic variable and the GDS stage.The study results will determine the efficacy of an intervention that addresses the extraordinary public health impact of late-stage ADRD and suffering due to symptom distress, burdensome treatments, and caregiver strain. While many caregivers prioritize comfort in late-stage ADRD, shared decision-making is rare. Hospitalization creates an opportunity for dementia-specific palliative care, and the study findings will inform care redesign to advance comprehensive dementia-specific palliative care plus transitional care.ClinicalTrials.gov NCT04948866. Registered on July 2, 2021." @default.
• W4387001872 created "2023-09-26" @default.
• W4387001872 creator A5001006844 @default.
• W4387001872 creator A5039973017 @default.
• W4387001872 creator A5046389080 @default.
• W4387001872 creator A5088391410 @default.
• W4387001872 creator A5088624996 @default.
• W4387001872 creator A5089086037 @default.
• W4387001872 creator A5090298551 @default.
• W4387001872 date "2023-09-25" @default.
• W4387001872 modified "2023-09-29" @default.
• W4387001872 title "Palliative care for persons with late-stage Alzheimer’s and related dementias and their caregivers: protocol for a randomized clinical trial" @default.
• W4387001872 cites W1555694414 @default.
• W4387001872 cites W1586208633 @default.
• W4387001872 cites W1586451147 @default.
• W4387001872 cites W1644143258 @default.
• W4387001872 cites W1863875520 @default.
• W4387001872 cites W1968322929 @default.
• W4387001872 cites W1969647049 @default.
• W4387001872 cites W1975970108 @default.
• W4387001872 cites W1976668870 @default.
• W4387001872 cites W1977983361 @default.
• W4387001872 cites W1979108564 @default.
• W4387001872 cites W1983132237 @default.
• W4387001872 cites W1989659245 @default.
• W4387001872 cites W1997791637 @default.
• W4387001872 cites W2000445173 @default.
• W4387001872 cites W2003235868 @default.
• W4387001872 cites W2013203952 @default.
• W4387001872 cites W2013335489 @default.
• W4387001872 cites W2021667480 @default.
• W4387001872 cites W2022956927 @default.
• W4387001872 cites W2037888665 @default.
• W4387001872 cites W2039546398 @default.
• W4387001872 cites W2053297661 @default.
• W4387001872 cites W2054085905 @default.
• W4387001872 cites W2055995430 @default.
• W4387001872 cites W2059214781 @default.
• W4387001872 cites W2070509642 @default.
• W4387001872 cites W2090795626 @default.
• W4387001872 cites W2103890330 @default.
• W4387001872 cites W2105121811 @default.
• W4387001872 cites W2108335346 @default.
• W4387001872 cites W2114146133 @default.
• W4387001872 cites W2114903161 @default.
• W4387001872 cites W2117469126 @default.
• W4387001872 cites W2119123819 @default.
• W4387001872 cites W2119731464 @default.
• W4387001872 cites W2124553793 @default.
• W4387001872 cites W2137762050 @default.
• W4387001872 cites W2139524347 @default.
• W4387001872 cites W2148080316 @default.
• W4387001872 cites W2150261076 @default.
• W4387001872 cites W2158938545 @default.
• W4387001872 cites W2165988683 @default.
• W4387001872 cites W2166023752 @default.
• W4387001872 cites W2170131723 @default.
• W4387001872 cites W2170302543 @default.
• W4387001872 cites W2558265756 @default.
• W4387001872 cites W2592972610 @default.
• W4387001872 cites W2619097621 @default.
• W4387001872 cites W2626539441 @default.
• W4387001872 cites W2724559116 @default.
• W4387001872 cites W2742856190 @default.
• W4387001872 cites W2742859105 @default.
• W4387001872 cites W2743399367 @default.
• W4387001872 cites W2779188219 @default.
• W4387001872 cites W2793452347 @default.
• W4387001872 cites W2897134714 @default.
• W4387001872 cites W2900828062 @default.
• W4387001872 cites W2940837416 @default.
• W4387001872 cites W2944434778 @default.
• W4387001872 cites W2952589228 @default.
• W4387001872 cites W2966863790 @default.
• W4387001872 doi "https://doi.org/10.1186/s13063-023-07614-4" @default.
• W4387001872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37743478" @default.
• W4387001872 hasPublicationYear "2023" @default.
• W4387001872 type Work @default.
• W4387001872 citedByCount "0" @default.
• W4387001872 crossrefType "journal-article" @default.
• W4387001872 hasAuthorship W4387001872A5001006844 @default.
• W4387001872 hasAuthorship W4387001872A5039973017 @default.
• W4387001872 hasAuthorship W4387001872A5046389080 @default.
• W4387001872 hasAuthorship W4387001872A5088391410 @default.
• W4387001872 hasAuthorship W4387001872A5088624996 @default.
• W4387001872 hasAuthorship W4387001872A5089086037 @default.
• W4387001872 hasAuthorship W4387001872A5090298551 @default.
• W4387001872 hasBestOaLocation W43870018721 @default.
• W4387001872 hasConcept C139265228 @default.
• W4387001872 hasConcept C141071460 @default.
• W4387001872 hasConcept C142724271 @default.
• W4387001872 hasConcept C159110408 @default.
• W4387001872 hasConcept C166957645 @default.
• W4387001872 hasConcept C168563851 @default.
• W4387001872 hasConcept C17744445 @default.
• W4387001872 hasConcept C199539241 @default.
• W4387001872 hasConcept C2776957806 @default.
• W4387001872 hasConcept C2777995714 @default.
• W4387001872 hasConcept C2778900529 @default.
• W4387001872 hasConcept C2779134260 @default.

• next