Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387002040> ?p ?o ?g. }
- W4387002040 abstract "ABSTRACT The stem/progenitor cell pool is indispensable for the development, homeostasis and regeneration of the gastric epithelium, owing to its defining ability to self-renew whilst supplying the various functional epithelial lineages needed to digest food efficiently. A detailed understanding of the intricacies and complexities surrounding the behaviours and roles of these stem cells offers insights, not only into the physiology of gastric epithelial development and maintenance, but also into the pathological consequences following aberrations in stem cell regulation. Here, we provide an insightful synthesis of the existing knowledge on gastric epithelial stem cell biology, including the in vitro and in vivo experimental techniques that have advanced such studies. We highlight the contributions of stem/progenitor cells towards patterning the developing stomach, specification of the differentiated cell lineages and maintenance of the mature epithelium during homeostasis and following injury. Finally, we discuss gaps in our understanding and identify key research areas for future work." @default.
- W4387002040 created "2023-09-26" @default.
- W4387002040 creator A5043581327 @default.
- W4387002040 creator A5073963216 @default.
- W4387002040 creator A5077132010 @default.
- W4387002040 creator A5091172060 @default.
- W4387002040 date "2023-09-15" @default.
- W4387002040 modified "2023-10-16" @default.
- W4387002040 title "Gastric epithelial stem cells in development, homeostasis and regeneration" @default.
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