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- W4387002736 abstract "Brain age, a measure of biological aging in the brain, has been linked to psychiatric illness, principally in adult populations. Components of socioeconomic status (SES) associate with differences in brain structure and psychiatric risk across the lifespan. This study aimed to investigate the influence of SES on brain aging in childhood and adolescence, a period of rapid neurodevelopment and peak onset for many psychiatric disorders. We reanalyzed data from the Healthy Brain Network to examine the influence of SES components (occupational prestige, public assistance enrollment, parent education, and household income-to-needs ratio [INR]) on relative brain age (RBA). Analyses included 470 youth (5-17 years; 61.3% men), self-identifying as White (55%), African American (15%), Hispanic (9%), or multiracial (17.2%). Household income was 3.95 ± 2.33 (mean ± SD) times the federal poverty threshold. RBA quantified differences between chronological age and brain age using covariation patterns of morphological features and total volumes. We also examined associations between RBA and psychiatric symptoms (Child Behavior Checklist [CBCL]). Models covaried for sex, scan location, and parent psychiatric diagnoses. In a linear regression, lower RBA is associated with lower parent occupational prestige (p = .01), lower public assistance enrollment (p = .03), and more parent psychiatric diagnoses (p = .01), but not parent education or INR. Lower parent occupational prestige (p = .02) and lower RBA (p = .04) are associated with higher CBCL anxious/depressed scores. Our findings underscore the importance of including SES components in developmental brain research. Delayed brain aging may represent a potential biological pathway from SES to psychiatric risk. (PsycInfo Database Record (c) 2023 APA, all rights reserved)." @default.
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- W4387002736 date "2023-09-25" @default.
- W4387002736 modified "2023-10-01" @default.
- W4387002736 title "Relative brain age is associated with socioeconomic status and anxiety/depression problems in youth." @default.
- W4387002736 doi "https://doi.org/10.1037/dev0001593" @default.
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- W4387002736 hasPublicationYear "2023" @default.
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