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- W4387004710 abstract "A fluorescent probe CTP2-IMC was designed for bioimaging of glutathione (GSH) in cancer cells with indomethacin (IMC), coumarin and bromide as the targeting group, fluorophore and receptor, respectively. Due to the π − π interaction between coumarin and IMC, CTP2-IMC mainly exists in the form of folded state in aqueous solution. The non-radiative transitions caused by the photo-induced electron transfer (PET) process from IMC to the fluorophore as well as the heavy-atom effect led to non-fluorescent of CTP2-IMC. The substitution of Br by GSH and unfolded conformation induced by IMC acceptor on cancer cells resulted in significant fluorescence enhancement, which enabled CTP2-IMC to bioimage GSH in cancer cells rather than in normal one." @default.
- W4387004710 created "2023-09-26" @default.
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- W4387004710 date "2024-01-01" @default.
- W4387004710 modified "2023-10-18" @default.
- W4387004710 title "A fluorescent probe for bioimaging of GSH in cancer cells" @default.
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- W4387004710 doi "https://doi.org/10.1016/j.saa.2023.123457" @default.
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