Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387008611> ?p ?o ?g. }
- W4387008611 endingPage "28" @default.
- W4387008611 startingPage "1" @default.
- W4387008611 abstract "AbstractRandomization procedures that enforce balance in prognostic factors, most commonly stratified randomization, are often employed in clinical trials. When the number of factors or factor levels is large, dynamic allocation procedures, such as the Pocock and Simon’s covariate-adaptive randomization (minimization) are preferred. In their ground-breaking work Ye and Shao (2020) identified two classes of covariate-adaptive randomization procedures. They have demonstrated theoretically that for these classes, when the model is misspecified, the robust score test (Lin and Wei, 1989) as well as the unstratified log-rank test used for analysis of time-to-event endpoints, are valid or conservative (Ye and Shao, 2020). This fact, however, was not established for minimization other than through simulations of survival endpoints. In this paper, we point out that the results of Ye and Shao can be expanded to a more general class of randomization procedures. We show, in part theoretically, in part through simulations of the within-strata imbalances, that minimization belongs to this class. Along the way we describe the asymptotic correlation matrix of the normalized within-stratum imbalances following minimization with equal prevalence of all strata. We expand the robust tests proposed by Ye and Shao for stratified randomization to minimization and examine their performance through simulations.Keywords: minimizationType I errorrobust survival analysis testsDisclaimerAs a service to authors and researchers we are providing this version of an accepted manuscript (AM). Copyediting, typesetting, and review of the resulting proofs will be undertaken on this manuscript before final publication of the Version of Record (VoR). During production and pre-press, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal relate to these versions also. AcknowledgementsThis research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. The authors would like to thank the anonymous reviewers whose recommendations substantially improved the paper.FundingThe author(s) reported there is no funding associated with the work featured in this article." @default.
- W4387008611 created "2023-09-26" @default.
- W4387008611 creator A5003964862 @default.
- W4387008611 creator A5081110161 @default.
- W4387008611 creator A5085661548 @default.
- W4387008611 date "2023-09-25" @default.
- W4387008611 modified "2023-09-26" @default.
- W4387008611 title "Validity of tests for time-to-event endpoints in studies with the Pocock and Simon covariate-adaptive randomization" @default.
- W4387008611 cites W1553818256 @default.
- W4387008611 cites W1570622790 @default.
- W4387008611 cites W1626634199 @default.
- W4387008611 cites W1969237525 @default.
- W4387008611 cites W1969965083 @default.
- W4387008611 cites W1984677252 @default.
- W4387008611 cites W2000366267 @default.
- W4387008611 cites W2001325558 @default.
- W4387008611 cites W2007316542 @default.
- W4387008611 cites W2007541822 @default.
- W4387008611 cites W2012658469 @default.
- W4387008611 cites W2013256551 @default.
- W4387008611 cites W2027940431 @default.
- W4387008611 cites W2034124226 @default.
- W4387008611 cites W2035560958 @default.
- W4387008611 cites W2042355708 @default.
- W4387008611 cites W2047311731 @default.
- W4387008611 cites W2061039755 @default.
- W4387008611 cites W2064353452 @default.
- W4387008611 cites W2065787672 @default.
- W4387008611 cites W2072159384 @default.
- W4387008611 cites W2075382525 @default.
- W4387008611 cites W2076438721 @default.
- W4387008611 cites W2085054454 @default.
- W4387008611 cites W2103116273 @default.
- W4387008611 cites W2108361431 @default.
- W4387008611 cites W2114306298 @default.
- W4387008611 cites W2131593307 @default.
- W4387008611 cites W2146699219 @default.
- W4387008611 cites W2149360415 @default.
- W4387008611 cites W2169571021 @default.
- W4387008611 cites W2301711657 @default.
- W4387008611 cites W2327670253 @default.
- W4387008611 cites W2467022164 @default.
- W4387008611 cites W2494442567 @default.
- W4387008611 cites W2803901697 @default.
- W4387008611 cites W2980033247 @default.
- W4387008611 cites W2990865727 @default.
- W4387008611 cites W3083711840 @default.
- W4387008611 cites W3102707029 @default.
- W4387008611 cites W3104544283 @default.
- W4387008611 cites W3121419567 @default.
- W4387008611 cites W3125732769 @default.
- W4387008611 cites W3134524818 @default.
- W4387008611 cites W3147894994 @default.
- W4387008611 cites W3182690093 @default.
- W4387008611 cites W4244480466 @default.
- W4387008611 cites W4245958676 @default.
- W4387008611 cites W4283069835 @default.
- W4387008611 cites W4385302907 @default.
- W4387008611 doi "https://doi.org/10.1080/19466315.2023.2261672" @default.
- W4387008611 hasPublicationYear "2023" @default.
- W4387008611 type Work @default.
- W4387008611 citedByCount "0" @default.
- W4387008611 crossrefType "journal-article" @default.
- W4387008611 hasAuthorship W4387008611A5003964862 @default.
- W4387008611 hasAuthorship W4387008611A5081110161 @default.
- W4387008611 hasAuthorship W4387008611A5085661548 @default.
- W4387008611 hasConcept C105795698 @default.
- W4387008611 hasConcept C119043178 @default.
- W4387008611 hasConcept C121332964 @default.
- W4387008611 hasConcept C126255220 @default.
- W4387008611 hasConcept C142724271 @default.
- W4387008611 hasConcept C147764199 @default.
- W4387008611 hasConcept C149782125 @default.
- W4387008611 hasConcept C154945302 @default.
- W4387008611 hasConcept C204243189 @default.
- W4387008611 hasConcept C2777212361 @default.
- W4387008611 hasConcept C2779662365 @default.
- W4387008611 hasConcept C33923547 @default.
- W4387008611 hasConcept C41008148 @default.
- W4387008611 hasConcept C50382708 @default.
- W4387008611 hasConcept C535046627 @default.
- W4387008611 hasConcept C62520636 @default.
- W4387008611 hasConcept C66339696 @default.
- W4387008611 hasConcept C71924100 @default.
- W4387008611 hasConceptScore W4387008611C105795698 @default.
- W4387008611 hasConceptScore W4387008611C119043178 @default.
- W4387008611 hasConceptScore W4387008611C121332964 @default.
- W4387008611 hasConceptScore W4387008611C126255220 @default.
- W4387008611 hasConceptScore W4387008611C142724271 @default.
- W4387008611 hasConceptScore W4387008611C147764199 @default.
- W4387008611 hasConceptScore W4387008611C149782125 @default.
- W4387008611 hasConceptScore W4387008611C154945302 @default.
- W4387008611 hasConceptScore W4387008611C204243189 @default.
- W4387008611 hasConceptScore W4387008611C2777212361 @default.
- W4387008611 hasConceptScore W4387008611C2779662365 @default.
- W4387008611 hasConceptScore W4387008611C33923547 @default.
- W4387008611 hasConceptScore W4387008611C41008148 @default.
- W4387008611 hasConceptScore W4387008611C50382708 @default.