Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387012959> ?p ?o ?g. }
- W4387012959 abstract "Abstract Military Veterans account for 8% of homeless individuals living in the United States. To highlight associations between history of homelessness and the gut microbiome, we compared the gut microbiome of Veterans who reported having a previous experience of homelessness to those from individuals who reported never having experienced a period of homelessness. Moreover, we examined the impact of the cumulative exposure of prior and current homelessness to understand possible associations between these experiences and the gut microbiome. Microbiome samples underwent genomic sequencing and were analyzed based on alpha diversity, beta diversity, and taxonomic differences. Additionally, demographic information, dietary data, and mental health history were collected. A lifetime history of homelessness was found to be associated with alcohol use disorder, substance use disorder, and healthy eating index compared to those without such a history. In terms of differences in gut microbiota, beta diversity was significantly different between Veterans that had experienced homelessness and Veterans that had never been homeless ( p = 0.047, Weighted UniFrac), while alpha diversity was similar. The microbial community differences were, in part, driven by a lower relative abundance of Akkermansia in Veterans that had experienced homelessness (mean ± SD; 1.07 ± 3.85) compared to Veterans that had never been homeless (2.02 ± 5.36) ( p = 0.014, ancom-bc2). Additional research is required to facilitate understanding regarding complex associations between homelessness, the gut microbiome, and mental and physical health conditions, with a focus on increasing understanding regarding the longitudinal impact of housing instability throughout the lifespan. Importance Although there are known stressors related to homelessness, as well as chronic health conditions experienced by those without stable housing, there has been limited work evaluating the associations between microbial community composition and homelessness. We analyzed, for the first time, bacterial gut microbiome associations among those with experiences of homelessness on alpha diversity, beta diversity, and taxonomic differences. Additionally, we characterized the influences of diet, demographic characteristics, military service history and mental health conditions on the microbiome of Veterans with and without any lifetime history of homelessness. Future longitudinal research to evaluate the complex relationships between homelessness, the gut microbiome, and mental health outcomes is recommended. Ultimately, differences in the gut microbiome of individuals experiencing and not experiencing homelessness could assist in identification of treatment targets to improve health outcomes." @default.
- W4387012959 created "2023-09-26" @default.
- W4387012959 creator A5008401627 @default.
- W4387012959 creator A5012144114 @default.
- W4387012959 creator A5013458083 @default.
- W4387012959 creator A5018617842 @default.
- W4387012959 creator A5020963967 @default.
- W4387012959 creator A5058136778 @default.
- W4387012959 creator A5058202212 @default.
- W4387012959 creator A5064708950 @default.
- W4387012959 creator A5072948125 @default.
- W4387012959 creator A5083142190 @default.
- W4387012959 date "2023-09-25" @default.
- W4387012959 modified "2023-09-30" @default.
- W4387012959 title "Association of homelessness and diet on the gut microbiome: A United States-Veteran Microbiome Project (US-VMP) study" @default.
- W4387012959 cites W2034082915 @default.
- W4387012959 cites W2034285706 @default.
- W4387012959 cites W2037882044 @default.
- W4387012959 cites W2049630090 @default.
- W4387012959 cites W2052554412 @default.
- W4387012959 cites W2055615060 @default.
- W4387012959 cites W2060038783 @default.
- W4387012959 cites W2103825558 @default.
- W4387012959 cites W2113750014 @default.
- W4387012959 cites W2123783128 @default.
- W4387012959 cites W2130148029 @default.
- W4387012959 cites W2142476463 @default.
- W4387012959 cites W2145452721 @default.
- W4387012959 cites W2153832854 @default.
- W4387012959 cites W2163250554 @default.
- W4387012959 cites W2166171121 @default.
- W4387012959 cites W2167948527 @default.
- W4387012959 cites W2274035836 @default.
- W4387012959 cites W2506900575 @default.
- W4387012959 cites W2591590445 @default.
- W4387012959 cites W2593591803 @default.
- W4387012959 cites W2604554951 @default.
- W4387012959 cites W2612604436 @default.
- W4387012959 cites W2612749242 @default.
- W4387012959 cites W2619680342 @default.
- W4387012959 cites W2620275008 @default.
- W4387012959 cites W2725472208 @default.
- W4387012959 cites W2738295910 @default.
- W4387012959 cites W2781047824 @default.
- W4387012959 cites W2789399981 @default.
- W4387012959 cites W2800461749 @default.
- W4387012959 cites W2888216390 @default.
- W4387012959 cites W2900900496 @default.
- W4387012959 cites W2901381087 @default.
- W4387012959 cites W2915542172 @default.
- W4387012959 cites W2938277062 @default.
- W4387012959 cites W2947402574 @default.
- W4387012959 cites W2954124338 @default.
- W4387012959 cites W2971235367 @default.
- W4387012959 cites W2977328964 @default.
- W4387012959 cites W2993908729 @default.
- W4387012959 cites W3008803822 @default.
- W4387012959 cites W3043062835 @default.
- W4387012959 cites W3044219890 @default.
- W4387012959 cites W3080122692 @default.
- W4387012959 cites W3082491122 @default.
- W4387012959 cites W3087302634 @default.
- W4387012959 cites W3133680096 @default.
- W4387012959 cites W3159303243 @default.
- W4387012959 cites W3180147035 @default.
- W4387012959 cites W3203179260 @default.
- W4387012959 cites W3209599082 @default.
- W4387012959 cites W4214943578 @default.
- W4387012959 cites W4220829338 @default.
- W4387012959 cites W4221107006 @default.
- W4387012959 cites W4224868124 @default.
- W4387012959 cites W4247665917 @default.
- W4387012959 cites W4320919870 @default.
- W4387012959 cites W4323347850 @default.
- W4387012959 doi "https://doi.org/10.1101/2023.09.22.559004" @default.
- W4387012959 hasPublicationYear "2023" @default.
- W4387012959 type Work @default.
- W4387012959 citedByCount "0" @default.
- W4387012959 crossrefType "posted-content" @default.
- W4387012959 hasAuthorship W4387012959A5008401627 @default.
- W4387012959 hasAuthorship W4387012959A5012144114 @default.
- W4387012959 hasAuthorship W4387012959A5013458083 @default.
- W4387012959 hasAuthorship W4387012959A5018617842 @default.
- W4387012959 hasAuthorship W4387012959A5020963967 @default.
- W4387012959 hasAuthorship W4387012959A5058136778 @default.
- W4387012959 hasAuthorship W4387012959A5058202212 @default.
- W4387012959 hasAuthorship W4387012959A5064708950 @default.
- W4387012959 hasAuthorship W4387012959A5072948125 @default.
- W4387012959 hasAuthorship W4387012959A5083142190 @default.
- W4387012959 hasBestOaLocation W43870129591 @default.
- W4387012959 hasConcept C118552586 @default.
- W4387012959 hasConcept C134362201 @default.
- W4387012959 hasConcept C143121216 @default.
- W4387012959 hasConcept C144024400 @default.
- W4387012959 hasConcept C149923435 @default.
- W4387012959 hasConcept C19165224 @default.
- W4387012959 hasConcept C2781316041 @default.
- W4387012959 hasConcept C60644358 @default.
- W4387012959 hasConcept C71924100 @default.
- W4387012959 hasConcept C74909509 @default.