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- W4387014710 abstract "Background: Prurigo nodularis (PN) is characterized by the presence of itchy nodules on the trunk/extremities, often accompanied by skin pain and sleep disruption. Psychometric validation and within-patient meaningful change thresholds for 3 patient-reported outcome instruments have been assessed in patients with PN: Worst Itch Numerical Rating Scale (WI-NRS), Skin Pain-NRS, and Sleep-NRS. The proportion of patients achieving clinically meaningful improvement in these scores was investigated in 2 pooled randomized, double-blind, placebo-controlled, phase 3 trials of dupilumab in adults with PN uncontrolled on topical therapies, LIBERTY-PN PRIME (NCT04183335) and PRIME2 (NCT04202679)." @default.
- W4387014710 created "2023-09-26" @default.
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- W4387014710 date "2023-09-01" @default.
- W4387014710 modified "2023-09-26" @default.
- W4387014710 title "42275 Dupilumab Improves Itch, Skin Pain, and Sleep in Adult Patients With Prurigo Nodularis (LIBERTY PN-PRIME and PRIME2)" @default.
- W4387014710 doi "https://doi.org/10.1016/j.jaad.2023.07.162" @default.
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