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- W4387015802 abstract "Background: Hyperpigmentation of the intimate area can cause discomfort in women, and can affect self-esteem and social and intimate relationships, such as exposure on the beach and in sexual intimacy. The aim of this study is to test a whitening cream produced with vitamin C, gallic acid, hexylresorcinol and niacinamide for the vulva and groin area under real conditions of use. Volunteers (n=24; age 19 to 57 years) with phototypes I to IV according to the Fitzpatrick scale used the cream twice a day for 90 days. Clinical and instrumental assessments were performed at 0, 30, 60 and 90 days. The acceptability and efficacy of the product were evaluated through the follow-up of dermatologists and gynecologists. The skin lightening parameter was evaluated by visual technique, colorimetry analysis using the Chroma Meter® equipment, color analysis by photographs and effectiveness perceived by the participant. The investigational product showed excellent cutaneous and gynecological tolerability, with no adverse events related to its use and no complaints or observations of burning or irritation. The cream promoted great whitening efficacy, with improvement of hyperpigmentation and skin roughness in all applied methodologies. A sexual quality of life questionnaire was carried out before and after the 90-day period of product use and the responses confirmed improved satisfaction and lubrication in the sexual act." @default.
- W4387015802 created "2023-09-26" @default.
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- W4387015802 date "2023-09-01" @default.
- W4387015802 modified "2023-09-26" @default.
- W4387015802 title "40657 Evaluation Of The Effectiveness Of An Intimate Whitening Cream Under Real Use Conditions" @default.
- W4387015802 doi "https://doi.org/10.1016/j.jaad.2023.07.661" @default.
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