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- W4387016002 abstract "Abstract Outdoor activity (OA) is considered the main modifiable risk factor for myopia development. Quantifying the association between Conjunctival Ultraviolet Autofluorescence (CUVAF) area and OA can be useful as a biomarker for myopia control. The purpose of this study is to quantify the association between CUVAF area and myopia. The articles included populations from different geographic areas (Europe/Asia/Australia) and ages. The bibliographic research was accomplished between June-August of 2022 with the following databases: MEDLINE/SCIENCE DIRECT/GOOGLE SCHOLAR/WEB OF SCIENCE/SCOPUS with all the terms related of conjunctival ultraviolet autofluorescence” (2006-2022). Cross-sectional and case-control studies were included. The differences between CUVAF area and the hours of OA performed by myopic and non-myopic patients and the correlation of OA with the size of the CUVAF area were analyzed. The meta-analysis of the CUVAF area between myopic and non-myopic patients showed statistically smaller areas (-3.30 mm²-CI95%[-5.5;-1.06]). Stratified sub-analysis by different geographic areas showed that Australia-Asia patients showed a greater difference in CUVAF area (-4.92 mm²-CI95%[-9.5;-0.29]) compared to Europe patients (-1.97 mm²;CI95%;-2.8;-1.14, p= 0.007). Myopic reported less OA vs non-myopic (-3.38 hours/week-CI95%[-4.6;-2.09]), and the correlation between CUVAF area and OA was 0.14 (CI95%[0.09;0.19]). A strong relationship was observed between CUVAF, myopia and OA in different studies and geographic locations. The importance of this validation is that CUVAF is a simple, fast and non-invasive quantitative method to evaluate the control of myopia." @default.
- W4387016002 created "2023-09-26" @default.
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- W4387016002 date "2023-09-25" @default.
- W4387016002 modified "2023-10-16" @default.
- W4387016002 title "Conjunctival Ultraviolet Autofluorescence as a Biomarker of Outdoor Exposure in Myopia: A Systematic Review and Meta-analysis." @default.
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- W4387016002 doi "https://doi.org/10.21203/rs.3.rs-3349393/v1" @default.
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