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- W4387016849 abstract "African trypanosomes show a remarkable ability to survive as extracellular parasites in the blood and tissue spaces of an infected mammal. Throughout the infection they are exposed to the molecules and cells of the immune system, including complement. In this opinion piece, we review decades-worth of evidence about how complement affects African trypanosomes. We highlight the discovery of a trypanosome receptor for complement C3 and we critically assess three recent studies which attempt to provide a structural and mechanistic view of how this receptor helps trypanosomes to survive in the presence of complement." @default.
- W4387016849 created "2023-09-26" @default.
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- W4387016849 date "2023-09-01" @default.
- W4387016849 modified "2023-10-05" @default.
- W4387016849 title "Trypanosomes and complement: more than one way to die?" @default.
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- W4387016849 doi "https://doi.org/10.1016/j.pt.2023.09.001" @default.
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