Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387021639> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W4387021639 abstract "Abstract Purpose Our objectives were to investigate the utility of 99m Tc-ethylenedicysteine-deoxyglucose (ECDG) in identifying active disease in the joints of patients with rheumatoid arthritis (RA), as well as to evaluate the biodistribution of this radiopharmaceutical. Methods A prospective study was conducted at the Department of Nuclear Medicine of the University of the Free State/Universitas Academic Hospital in Bloemfontein, South Africa. Twenty-two participants from the rheumatology department diagnosed with RA according to the ACR/EULAR classification criteria were enrolled. Participants were injected with 20–25 mCi of 99m Tc-ECDG. Flow, blood pool, whole body, delayed static, and SPECT/CT images were acquired. Known sites of disease were qualitatively assessed for intensity of uptake, and disease severity was graded (Grade 0–3). Results Twenty-two participants were studied. The median (interquartile range) age was 59 (49–68) years, and the majority ( n = 21; 95.5%) were females. There was abnormal increased uptake of 99m Tc-ECDG noted in majority of the sites of known disease, including unknown sites. SPECT/CT imaging localized radiotracer uptake specifically to the synovial space. Similar biodistribution of radiotracer was noted in all patients, irrespective of disease severity or fasting status. Conclusion 99m Tc-ECDG can efficiently assess disease activity in the joints of patients with RA. It accumulates in sites of both clinical and subclinical disease and might be a very useful tool for the rheumatologist in the management of patients with RA." @default.
- W4387021639 created "2023-09-26" @default.
- W4387021639 creator A5015663017 @default.
- W4387021639 creator A5037869397 @default.
- W4387021639 creator A5045224180 @default.
- W4387021639 creator A5066483347 @default.
- W4387021639 creator A5077525618 @default.
- W4387021639 creator A5085267368 @default.
- W4387021639 creator A5091228836 @default.
- W4387021639 date "2023-09-25" @default.
- W4387021639 modified "2023-09-26" @default.
- W4387021639 title "The Biodistribution and Utility of 99mTc-Ethylenedicysteine-Deoxyglucose (99mTc-Glucosamine) in the Identification of Active Disease in Patients with Rheumatoid Arthritis—a Single Center Prospective Study" @default.
- W4387021639 cites W1506611034 @default.
- W4387021639 cites W1997646751 @default.
- W4387021639 cites W2032362610 @default.
- W4387021639 cites W2043609242 @default.
- W4387021639 cites W2070137023 @default.
- W4387021639 cites W2071992973 @default.
- W4387021639 cites W2103099020 @default.
- W4387021639 cites W2141620928 @default.
- W4387021639 cites W2151153432 @default.
- W4387021639 cites W2330545785 @default.
- W4387021639 cites W2417465353 @default.
- W4387021639 cites W2529651453 @default.
- W4387021639 cites W2790894316 @default.
- W4387021639 cites W2797494384 @default.
- W4387021639 cites W3000091148 @default.
- W4387021639 cites W3006080604 @default.
- W4387021639 cites W4240547518 @default.
- W4387021639 doi "https://doi.org/10.1007/s13139-023-00823-4" @default.
- W4387021639 hasPublicationYear "2023" @default.
- W4387021639 type Work @default.
- W4387021639 citedByCount "0" @default.
- W4387021639 crossrefType "journal-article" @default.
- W4387021639 hasAuthorship W4387021639A5015663017 @default.
- W4387021639 hasAuthorship W4387021639A5037869397 @default.
- W4387021639 hasAuthorship W4387021639A5045224180 @default.
- W4387021639 hasAuthorship W4387021639A5066483347 @default.
- W4387021639 hasAuthorship W4387021639A5077525618 @default.
- W4387021639 hasAuthorship W4387021639A5085267368 @default.
- W4387021639 hasAuthorship W4387021639A5091228836 @default.
- W4387021639 hasBestOaLocation W43870216391 @default.
- W4387021639 hasConcept C113280763 @default.
- W4387021639 hasConcept C119060515 @default.
- W4387021639 hasConcept C126322002 @default.
- W4387021639 hasConcept C188816634 @default.
- W4387021639 hasConcept C198451711 @default.
- W4387021639 hasConcept C2777575956 @default.
- W4387021639 hasConcept C2779134260 @default.
- W4387021639 hasConcept C2989005 @default.
- W4387021639 hasConcept C71924100 @default.
- W4387021639 hasConceptScore W4387021639C113280763 @default.
- W4387021639 hasConceptScore W4387021639C119060515 @default.
- W4387021639 hasConceptScore W4387021639C126322002 @default.
- W4387021639 hasConceptScore W4387021639C188816634 @default.
- W4387021639 hasConceptScore W4387021639C198451711 @default.
- W4387021639 hasConceptScore W4387021639C2777575956 @default.
- W4387021639 hasConceptScore W4387021639C2779134260 @default.
- W4387021639 hasConceptScore W4387021639C2989005 @default.
- W4387021639 hasConceptScore W4387021639C71924100 @default.
- W4387021639 hasFunder F4320322870 @default.
- W4387021639 hasFunder F4320335132 @default.
- W4387021639 hasLocation W43870216391 @default.
- W4387021639 hasOpenAccess W4387021639 @default.
- W4387021639 hasPrimaryLocation W43870216391 @default.
- W4387021639 hasRelatedWork W2061253854 @default.
- W4387021639 hasRelatedWork W2082406232 @default.
- W4387021639 hasRelatedWork W2156283049 @default.
- W4387021639 hasRelatedWork W2316954211 @default.
- W4387021639 hasRelatedWork W2326094713 @default.
- W4387021639 hasRelatedWork W2427075784 @default.
- W4387021639 hasRelatedWork W2617939361 @default.
- W4387021639 hasRelatedWork W2761967325 @default.
- W4387021639 hasRelatedWork W4210646529 @default.
- W4387021639 hasRelatedWork W4236980849 @default.
- W4387021639 isParatext "false" @default.
- W4387021639 isRetracted "false" @default.
- W4387021639 workType "article" @default.