Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387021981> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4387021981 abstract "The traditional Chinese medicine Aralia elata (Miq.) seem., also known as Aralia mandshurica, has the effect of tonifying qi and calming the mind, strengthening the essence and tonifying the kidneys, and dispelling wind and invigorating blood circulation, and is used in the treatment of neurasthenia, yang deficiency and Qi deficiency, kidney Qi deficiency, spleen Yang deficiency, water-dampness stagnation, thirst, and bruises, etc. Aralia elata saponins are the main material basis for its pharmacological effects. From the perspective of modern pharmacological science Aralia elata has a wide range of effects, including anti-myocardial ischaemia and alleviation of secondary myocardium ischemic reperfusion injury by regulating ionic homeostasis, anti-tumor by inhibiting proliferation, promoting apoptosis and enhancing immunity, hypoglycaemia and lipid lowering by regulating glucose and lipid metabolism, and hepato-protective, neuroprotective, anti-inflammatory/analgesic effects. The studies on pharmacological mechanism of Aralia elata will be conducive to its development and application in the future. This article reviews the research progress of Aralia elata domestically and internationally in the last two decades, and proposes new directions for its further pharmacological research.中国传统药材辽东楤木［Aralia elata （Miq.） Seem.］又称龙牙楤木，具有“补气安神，强精滋肾，祛风活血”的功效，用于治疗神经衰弱、阳虚气弱、肾气不足、脾阳虚衰之水湿停滞、消渴、跌打损伤等症。楤木皂苷类化合物是其发挥药理作用的主要物质基础。辽东楤木具有广泛的现代药理学作用，主要包括通过调控离子稳态及抑制炎症发挥抗心肌缺血来缓解继发性心肌缺血再灌注损伤的作用；通过抑制肿瘤细胞增殖促进肿瘤细胞凋亡及增强机体免疫来发挥抗肿瘤作用；通过调控机体糖脂代谢发挥降血糖、调血脂药理作用；以及保肝护肝、神经保护和抗炎、镇痛作用。未来，辽东楤木药理作用机制的深入研究将有利于促进其开发及利用。本文综述了国内外近二十年来对辽东楤木的相关研究，并提出了针对辽东楤木的药理研究新思路，旨在为同行提供参考。." @default.
- W4387021981 created "2023-09-26" @default.
- W4387021981 creator A5092936614 @default.
- W4387021981 creator A5092936615 @default.
- W4387021981 creator A5092936616 @default.
- W4387021981 date "2023-09-01" @default.
- W4387021981 modified "2023-10-08" @default.
- W4387021981 title "Research progress in pharmacological property of <italic>Aralia elata</italic>" @default.
- W4387021981 cites W1978045066 @default.
- W4387021981 cites W1985405659 @default.
- W4387021981 cites W1991132126 @default.
- W4387021981 cites W1992665990 @default.
- W4387021981 cites W2005870075 @default.
- W4387021981 cites W2022993390 @default.
- W4387021981 cites W2025001269 @default.
- W4387021981 cites W2036751476 @default.
- W4387021981 cites W2049935736 @default.
- W4387021981 cites W2050418795 @default.
- W4387021981 cites W2073804093 @default.
- W4387021981 cites W2076259660 @default.
- W4387021981 cites W2078405223 @default.
- W4387021981 cites W2091794990 @default.
- W4387021981 cites W2134236809 @default.
- W4387021981 cites W2157295602 @default.
- W4387021981 cites W2161442235 @default.
- W4387021981 cites W2170551352 @default.
- W4387021981 cites W2479827938 @default.
- W4387021981 cites W2574179058 @default.
- W4387021981 cites W2587134464 @default.
- W4387021981 cites W2590961242 @default.
- W4387021981 cites W2733838286 @default.
- W4387021981 cites W2765451325 @default.
- W4387021981 cites W2767392461 @default.
- W4387021981 cites W2801907975 @default.
- W4387021981 cites W2803346651 @default.
- W4387021981 cites W2890557788 @default.
- W4387021981 cites W2895182352 @default.
- W4387021981 cites W2917047802 @default.
- W4387021981 cites W2944419489 @default.
- W4387021981 cites W2997242667 @default.
- W4387021981 cites W3028455568 @default.
- W4387021981 cites W3094053673 @default.
- W4387021981 cites W3095862393 @default.
- W4387021981 cites W3212366636 @default.
- W4387021981 cites W4200050093 @default.
- W4387021981 cites W4309510350 @default.
- W4387021981 doi "https://doi.org/10.3724/zdxbyxb-2023-0147" @default.
- W4387021981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37802964" @default.
- W4387021981 hasPublicationYear "2023" @default.
- W4387021981 type Work @default.
- W4387021981 citedByCount "0" @default.
- W4387021981 crossrefType "journal-article" @default.
- W4387021981 hasAuthorship W4387021981A5092936614 @default.
- W4387021981 hasAuthorship W4387021981A5092936615 @default.
- W4387021981 hasAuthorship W4387021981A5092936616 @default.
- W4387021981 hasConcept C25498285 @default.
- W4387021981 hasConcept C2985453986 @default.
- W4387021981 hasConcept C556039675 @default.
- W4387021981 hasConcept C71924100 @default.
- W4387021981 hasConcept C98274493 @default.
- W4387021981 hasConceptScore W4387021981C25498285 @default.
- W4387021981 hasConceptScore W4387021981C2985453986 @default.
- W4387021981 hasConceptScore W4387021981C556039675 @default.
- W4387021981 hasConceptScore W4387021981C71924100 @default.
- W4387021981 hasConceptScore W4387021981C98274493 @default.
- W4387021981 hasLocation W43870219811 @default.
- W4387021981 hasLocation W43870219812 @default.
- W4387021981 hasOpenAccess W4387021981 @default.
- W4387021981 hasPrimaryLocation W43870219811 @default.
- W4387021981 hasRelatedWork W1506200166 @default.
- W4387021981 hasRelatedWork W1995515455 @default.
- W4387021981 hasRelatedWork W2048182022 @default.
- W4387021981 hasRelatedWork W2080531066 @default.
- W4387021981 hasRelatedWork W2604872355 @default.
- W4387021981 hasRelatedWork W2748952813 @default.
- W4387021981 hasRelatedWork W2899084033 @default.
- W4387021981 hasRelatedWork W3031052312 @default.
- W4387021981 hasRelatedWork W3032375762 @default.
- W4387021981 hasRelatedWork W3108674512 @default.
- W4387021981 isParatext "false" @default.
- W4387021981 isRetracted "false" @default.
- W4387021981 workType "article" @default.