FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387026902> ?p ?o ?g. }

• W4387026902 endingPage "127091" @default.
• W4387026902 startingPage "127091" @default.
• W4387026902 abstract "Brain cancer is the major reason of cancer-relevant deaths every year, as it is the most challenging cancer to treat and drug delivery. Quercetin (QUR), as a flavonoid substance found in plants and fruits, has good anticancer and medicinal effects on brain tumors, but its low stability and bioavailability as well as the blood-brain barrier (BBB), prevent it from reaching brain tumors. This research has introduced a nanocomposite made of biocompatible polymers, chitosan, and carboxymethyl cellulose. This co- biopolymer's mechanical and chemical properties and drug-loading capacity have been improved by adding zinc oxide nanoparticles (ZnO NPs). In addition, graphene quantum dots (GQDs) were used to improve the chemical properties as well as the ability to penetrate the BBB. The CS/CMC/GQDs/ZnO@QUR nanocomposites have nanoneedle structures with an average size of 219.38 ± 5.21 nm and a zeta potential of −53 mV. The morphology, chemical bonds, and crystallinity of the nanocomposite were examined by FE-SEM, FTIR, and XRD analyses, respectively. By examining the release of QUR, it became apparent that the half-drug release takes about 72 h, which has a much more controlled release than other QUR carriers. Further, the MTT test on U-87 MG and L929 cell lines suggested that this nanocomposite has good anticancer properties and low cytotoxicity compared to the free QUR." @default.
• W4387026902 created "2023-09-26" @default.
• W4387026902 creator A5069053014 @default.
• W4387026902 creator A5079968507 @default.
• W4387026902 creator A5092937743 @default.
• W4387026902 date "2023-12-01" @default.
• W4387026902 modified "2023-10-02" @default.
• W4387026902 title "Co-biopolymer of chitosan/carboxymethyl cellulose hydrogel improved by zinc oxide and graphene quantum dots nanoparticles as pH-sensitive nanocomposite for quercetin delivery to brain cancer treatment" @default.
• W4387026902 cites W1923009415 @default.
• W4387026902 cites W1932135775 @default.
• W4387026902 cites W1981512405 @default.
• W4387026902 cites W1983327991 @default.
• W4387026902 cites W1988759097 @default.
• W4387026902 cites W1997986030 @default.
• W4387026902 cites W2000373597 @default.
• W4387026902 cites W2009615797 @default.
• W4387026902 cites W2030133707 @default.
• W4387026902 cites W2030911321 @default.
• W4387026902 cites W2044013857 @default.
• W4387026902 cites W2046700476 @default.
• W4387026902 cites W2054375471 @default.
• W4387026902 cites W2056098235 @default.
• W4387026902 cites W2066294256 @default.
• W4387026902 cites W2072647281 @default.
• W4387026902 cites W2085453305 @default.
• W4387026902 cites W2087468617 @default.
• W4387026902 cites W2174999755 @default.
• W4387026902 cites W2234155771 @default.
• W4387026902 cites W2235723738 @default.
• W4387026902 cites W2507919919 @default.
• W4387026902 cites W2513971504 @default.
• W4387026902 cites W2570771273 @default.
• W4387026902 cites W2570900469 @default.
• W4387026902 cites W2775268498 @default.
• W4387026902 cites W2857430289 @default.
• W4387026902 cites W2893976390 @default.
• W4387026902 cites W2913886150 @default.
• W4387026902 cites W2944262032 @default.
• W4387026902 cites W2947563639 @default.
• W4387026902 cites W3000702874 @default.
• W4387026902 cites W3010132981 @default.
• W4387026902 cites W3011990170 @default.
• W4387026902 cites W3049697895 @default.
• W4387026902 cites W3083579853 @default.
• W4387026902 cites W3084367255 @default.
• W4387026902 cites W3086086307 @default.
• W4387026902 cites W3088792706 @default.
• W4387026902 cites W3090640195 @default.
• W4387026902 cites W3091445330 @default.
• W4387026902 cites W3097492009 @default.
• W4387026902 cites W3099409659 @default.
• W4387026902 cites W3119952098 @default.
• W4387026902 cites W3157900597 @default.
• W4387026902 cites W3177014410 @default.
• W4387026902 cites W3198922546 @default.
• W4387026902 cites W3199148790 @default.
• W4387026902 cites W3201507711 @default.
• W4387026902 cites W3209238951 @default.
• W4387026902 cites W3216355461 @default.
• W4387026902 cites W4205567487 @default.
• W4387026902 cites W4210285715 @default.
• W4387026902 cites W4220807796 @default.
• W4387026902 cites W4224274633 @default.
• W4387026902 cites W4224313580 @default.
• W4387026902 cites W4225163252 @default.
• W4387026902 cites W4284992363 @default.
• W4387026902 cites W4292859984 @default.
• W4387026902 cites W4295004976 @default.
• W4387026902 cites W4295338757 @default.
• W4387026902 cites W4306765111 @default.
• W4387026902 cites W4307945513 @default.
• W4387026902 cites W4308045559 @default.
• W4387026902 cites W4311730115 @default.
• W4387026902 cites W4313593854 @default.
• W4387026902 cites W4319460656 @default.
• W4387026902 cites W4320081164 @default.
• W4387026902 cites W4321487130 @default.
• W4387026902 cites W4322486693 @default.
• W4387026902 cites W4323817167 @default.
• W4387026902 cites W4327737077 @default.
• W4387026902 cites W4362575589 @default.
• W4387026902 cites W4362631128 @default.
• W4387026902 cites W4366818001 @default.
• W4387026902 cites W4377696082 @default.
• W4387026902 doi "https://doi.org/10.1016/j.ijbiomac.2023.127091" @default.
• W4387026902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37758113" @default.
• W4387026902 hasPublicationYear "2023" @default.
• W4387026902 type Work @default.
• W4387026902 citedByCount "0" @default.
• W4387026902 crossrefType "journal-article" @default.
• W4387026902 hasAuthorship W4387026902A5069053014 @default.
• W4387026902 hasAuthorship W4387026902A5079968507 @default.
• W4387026902 hasAuthorship W4387026902A5092937743 @default.
• W4387026902 hasConcept C127413603 @default.
• W4387026902 hasConcept C13245373 @default.
• W4387026902 hasConcept C13965031 @default.
• W4387026902 hasConcept C155672457 @default.
• W4387026902 hasConcept C159985019 @default.

• next