Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387033250> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4387033250 abstract "The incidence of type 2 diabetes in China has exhibited an increasing trend, including younger individuals, over the past years. Early-onset type 2 diabetes (EOT2D) refers to diabetes diagnosed before 40 years of age. These patients have poor metabolic control and are highly susceptible to diabetic complications, which poses challenges for treatment. However, few studies have reported on the treatment of EOT2D. We determined clinical features and trends in drug use in patients with type 2 diabetes mellitus (T2DM).This retrospective study was performed at the Endocrinology Ward, Peking Union Medical College Hospital (PUMCH). Diabetes was used when searching PUMCH's Electronic Medical Record Analytical Database to obtain clinical data of patients between January 2013 and May 2022.The analysis included 1590 patients with T2DM. Among them, 609 (38.3%) had EOT2D. Compared with late-onset type 2 diabetes (LOT2D) patients, EOT2D patients exhibited worse glycemic control and higher body weight and lipid levels despite significant age differences. EOT2D patients also had a higher risk of diabetic retinopathy and nephropathy. Under the general trend of increasing use of dipeptidylpeptidase-4 inhibitors, sodium-glucose cotransporter-2 inhibitors, and glucagon-like peptide-1 agonists, patients with EOT2D were more likely to use organ-protective drugs.Compared with LOT2D patients, EOT2D patients have a longer course of diabetes, worse metabolic control, and a higher rate of developing microvascular complications. The administration of combined therapy, including new agents, may require consideration when selecting hypoglycemic agents for treating EOT2D." @default.
- W4387033250 created "2023-09-27" @default.
- W4387033250 creator A5021252050 @default.
- W4387033250 creator A5037504776 @default.
- W4387033250 creator A5043994794 @default.
- W4387033250 creator A5086418698 @default.
- W4387033250 date "2023-09-26" @default.
- W4387033250 modified "2023-10-15" @default.
- W4387033250 title "Ten‐year clinical characteristics of patients with early‐onset type 2 diabetes: A single‐center experience in China" @default.
- W4387033250 cites W1538553036 @default.
- W4387033250 cites W2067086255 @default.
- W4387033250 cites W2112061753 @default.
- W4387033250 cites W2130266732 @default.
- W4387033250 cites W2150959326 @default.
- W4387033250 cites W2605748423 @default.
- W4387033250 cites W2760470116 @default.
- W4387033250 cites W3020528808 @default.
- W4387033250 cites W4200533463 @default.
- W4387033250 cites W4210624864 @default.
- W4387033250 doi "https://doi.org/10.1111/1753-0407.13477" @default.
- W4387033250 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37750029" @default.
- W4387033250 hasPublicationYear "2023" @default.
- W4387033250 type Work @default.
- W4387033250 citedByCount "0" @default.
- W4387033250 crossrefType "journal-article" @default.
- W4387033250 hasAuthorship W4387033250A5021252050 @default.
- W4387033250 hasAuthorship W4387033250A5037504776 @default.
- W4387033250 hasAuthorship W4387033250A5043994794 @default.
- W4387033250 hasAuthorship W4387033250A5086418698 @default.
- W4387033250 hasBestOaLocation W43870332501 @default.
- W4387033250 hasConcept C120665830 @default.
- W4387033250 hasConcept C121332964 @default.
- W4387033250 hasConcept C126322002 @default.
- W4387033250 hasConcept C134018914 @default.
- W4387033250 hasConcept C141071460 @default.
- W4387033250 hasConcept C195910791 @default.
- W4387033250 hasConcept C2777180221 @default.
- W4387033250 hasConcept C2778313320 @default.
- W4387033250 hasConcept C2779829184 @default.
- W4387033250 hasConcept C2780473172 @default.
- W4387033250 hasConcept C2781184683 @default.
- W4387033250 hasConcept C2910068830 @default.
- W4387033250 hasConcept C555293320 @default.
- W4387033250 hasConcept C61511704 @default.
- W4387033250 hasConcept C71924100 @default.
- W4387033250 hasConceptScore W4387033250C120665830 @default.
- W4387033250 hasConceptScore W4387033250C121332964 @default.
- W4387033250 hasConceptScore W4387033250C126322002 @default.
- W4387033250 hasConceptScore W4387033250C134018914 @default.
- W4387033250 hasConceptScore W4387033250C141071460 @default.
- W4387033250 hasConceptScore W4387033250C195910791 @default.
- W4387033250 hasConceptScore W4387033250C2777180221 @default.
- W4387033250 hasConceptScore W4387033250C2778313320 @default.
- W4387033250 hasConceptScore W4387033250C2779829184 @default.
- W4387033250 hasConceptScore W4387033250C2780473172 @default.
- W4387033250 hasConceptScore W4387033250C2781184683 @default.
- W4387033250 hasConceptScore W4387033250C2910068830 @default.
- W4387033250 hasConceptScore W4387033250C555293320 @default.
- W4387033250 hasConceptScore W4387033250C61511704 @default.
- W4387033250 hasConceptScore W4387033250C71924100 @default.
- W4387033250 hasFunder F4320321001 @default.
- W4387033250 hasFunder F4320322919 @default.
- W4387033250 hasFunder F4320325902 @default.
- W4387033250 hasLocation W43870332501 @default.
- W4387033250 hasLocation W43870332502 @default.
- W4387033250 hasOpenAccess W4387033250 @default.
- W4387033250 hasPrimaryLocation W43870332501 @default.
- W4387033250 hasRelatedWork W1969034278 @default.
- W4387033250 hasRelatedWork W2049859140 @default.
- W4387033250 hasRelatedWork W2095529597 @default.
- W4387033250 hasRelatedWork W2372099272 @default.
- W4387033250 hasRelatedWork W2884373074 @default.
- W4387033250 hasRelatedWork W2889207237 @default.
- W4387033250 hasRelatedWork W2907238362 @default.
- W4387033250 hasRelatedWork W2978619802 @default.
- W4387033250 hasRelatedWork W3164757844 @default.
- W4387033250 hasRelatedWork W3165096768 @default.
- W4387033250 isParatext "false" @default.
- W4387033250 isRetracted "false" @default.
- W4387033250 workType "article" @default.