Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387035906> ?p ?o ?g. }
- W4387035906 endingPage "152272" @default.
- W4387035906 startingPage "152272" @default.
- W4387035906 abstract "In recent years, identifying the pathophysiologic mechanisms underlying autoimmune arthritides and systematic diseases has led to the use of biological drugs. The primary targets of those biological therapies are cytokines, B cells, and co-stimulation molecules. So far, these targeted therapies have shown good clinical improvement and an acceptable toxicity profile. However, by blocking components of an intact immune system, autoimmune phenomena and paradoxical inflammation have emerged, and among them many cutaneous immune-related adverse events (irAEs). In this article, we review the current state of knowledge on the clinical features and mechanisms of specific cutaneous irAEs observed during treatment with biological therapies. Among those, psoriatic skin lesions are the most commonly observed. Herein, we also report new cases of cutaneous irAEs recently seen in our clinic to help physicians treating inflammatory arthritides recognize cutaneous irAEs early and better manage patients receiving biologic therapies." @default.
- W4387035906 created "2023-09-27" @default.
- W4387035906 creator A5002536319 @default.
- W4387035906 creator A5033852752 @default.
- W4387035906 creator A5033945739 @default.
- W4387035906 creator A5054058404 @default.
- W4387035906 date "2023-12-01" @default.
- W4387035906 modified "2023-10-05" @default.
- W4387035906 title "Cutaneous immune-related phenomena in patients with inflammatory arthritides treated with biological therapies: Clinical and pathophysiological considerations" @default.
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