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- W4387053039 abstract "Abstract Nanotechnology has been widely used in drug design in recent years, showing great potential and advantages in tumor therapy. However, the application of most traditional nanomedicines is still limited by low drug loading rate, poor targeting ability, and systemic toxicity. Based on the characteristics of tumor microenvironments, numerous studies indicate that the construction of stimuli‐responsive nanocarriers can effectively solve the above problems by improving delivery efficiency, reducing side effects, and enhancing targeting. A significant feature of responsive nanocarriers is that they can release and activate drugs at specific sites under stimulus, including internal stimuli (e.g., pH, reactive oxygen species (ROS), glutathione (GSH), enzyme, hypoxia, adenosine‐triphosphate (ATP), etc.) and external stimuli (e.g., light, thermo, ultrasound, etc.). Of note, learning about various pathways of responses can enable researchers to effectively design responsive nanocarriers for tumor therapy. Herein, this review focuses on the stimuli‐responsive strategies of nanocarriers for tumor therapy. In addition, the role of responsive nanocarriers in synergistic tumor therapy is also discussed. The expectation of this review is to provide ideas for the design of practical and effective responsive nanocarriers." @default.
- W4387053039 created "2023-09-27" @default.
- W4387053039 creator A5000601331 @default.
- W4387053039 creator A5003912075 @default.
- W4387053039 creator A5018655169 @default.
- W4387053039 creator A5024036072 @default.
- W4387053039 creator A5047717973 @default.
- W4387053039 creator A5048457346 @default.
- W4387053039 creator A5084142619 @default.
- W4387053039 date "2023-10-08" @default.
- W4387053039 modified "2023-10-18" @default.
- W4387053039 title "Nanomedicines Based on Responsive Nanocarriers for Cancer Therapy" @default.
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