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• W4387053880 abstract "PURPOSE: Blood pressure and peak oxygen uptake (VO2peak) are independent predictors of all-cause and cardiovascular mortality. Individuals with a VO2peak of 8 METs or greater have decreased risk of cardiovascular disease compared to those with a VO2peak less than 8 METs. Increasing physical activity (PA) in inactive adults is associated with improvements in cardiorespiratory fitness (CRF) and blood pressure (BP), however only 10% of adults in the United States meet PA guidelines. There is limited data investigating the relationship between CRF and the odds of having elevated blood pressure (SBP ≥ 120 and/or DBP ≥ 80) or hypertension (SBP ≥ 140 and/or DBP ≥ 90) Therefore, we determined the odds of having elevated blood pressure or hypertension in individuals dichotomized based on CRF (< 8METS or ≥ 8 METS). METHODS: Inactive (as determined by IPAQ and confirmed via accelerometer) individuals (N = 518) underwent BP and anthropometric testing followed by a treadmill-based graded exercise test (modified Balke protocol) with ventilatory gas exchange assessment to determine VO2peak. Only valid VO2peak tests (≥90% age-predicted heart rate max, RER > 1.05) were used for analyses. Age and sex adjusted logistic regression examined the relationship of CRF status with odds of normal BP, elevated BP, or hypertension. Data are presented as means ± SD. α was set at 0.05. RESULTS: Three hundred and seventy-five individuals met the criteria for a valid VO2peak test (age = 44.8 ± 9.1 years; BMI = 32.9 ± 6.6; VO2peak = 24.5 ± 4.8 mL/kg/min; SBP = 121 ± 13; DBP = 81 ± 10 mmHg; Males/Females = 124/251). One-hundred and twenty-seven subjects had normal BP, 164 had elevated BP, and 84 individuals were hypertensive. Those with CRF < 8 METs did not have different odds of having elevated BP (OR = 1.3, 95% CI: 0.7 - 2.4, p = 0.33). However, those with CRF < 8 METs were more likely to be hypertensive compared to individuals with CRF ≥ 8 METs (OR = 2.5, 95% CI: 1.2 - 5.2, p = 0.01). CONCLUSIONS: The present study found that low CRF in inactive adults was associated with increased odds of being hypertensive. This underscores the higher cardiovascular disease risk burden in this population and the need for targeted interventions to optimize outcomes. Supported by R01CA198915" @default.
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• W4387053880 date "2023-09-01" @default.
• W4387053880 modified "2023-09-27" @default.
• W4387053880 title "Cardiorespiratory Fitness As A Predictor Of Hypertension Status In Inactive Adults" @default.
• W4387053880 doi "https://doi.org/10.1249/01.mss.0000986928.56470.44" @default.
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