FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387059637> ?p ?o ?g. }

• W4387059637 abstract "HLA-B27 positivity is normal in patients undergoing rheumatic diseases. The diagnosis of many diseases requires an HLA-B27 examination.This study screened totally 1503 patients who underwent HLA-B27 examination, liver/kidney function tests, and complete blood routine examination in First Affiliated Hospital of Guangxi Medical University. The training cohort included 509 cases with HLA-B27 positivity whereas 611 with HLA-B27 negativity. In addition, validation cohort included 147 cases with HLA-B27 positivity whereas 236 with HLA-B27 negativity. In this study, 3 ML approaches, namely, LASSO, support vector machine (SVM) recursive feature elimination and random forest, were adopted for screening feature variables. Subsequently, to acquire the prediction model, the intersection was selected. Finally, differences among 148 cases with HLA-B27 positivity and negativity suffering from ankylosing spondylitis (AS) were investigated.Six factors, namely red blood cell count, human major compatibility complex, mean platelet volume, albumin/globulin ratio (ALB/GLB), prealbumin, and bicarbonate radical, were chosen with the aim of constructing the diagnostic nomogram using ML methods. For training queue, nomogram curve exhibited the value of area under the curve (AUC) of 0.8254496, and C-value of the model was 0.825. Moreover, nomogram C-value of the validation queue was 0.853, and the AUC value was 0.852675. Furthermore, a significant decrease in the ALB/GLB was noted among cases with HLA-B27 positivity and AS cases.To conclude, the proposed ML model can effectively predict HLA-B27 and help doctors in the diagnosis of various immune diseases." @default.
• W4387059637 created "2023-09-27" @default.
• W4387059637 creator A5000080255 @default.
• W4387059637 creator A5006833753 @default.
• W4387059637 creator A5012777958 @default.
• W4387059637 creator A5015255981 @default.
• W4387059637 creator A5019560977 @default.
• W4387059637 creator A5021294207 @default.
• W4387059637 creator A5021585653 @default.
• W4387059637 creator A5023403656 @default.
• W4387059637 creator A5030972493 @default.
• W4387059637 creator A5045551132 @default.
• W4387059637 creator A5053911985 @default.
• W4387059637 creator A5056428506 @default.
• W4387059637 creator A5058544003 @default.
• W4387059637 creator A5072719400 @default.
• W4387059637 creator A5086856805 @default.
• W4387059637 date "2023-09-26" @default.
• W4387059637 modified "2023-10-11" @default.
• W4387059637 title "Development and validation of a machine learning-based nomogram for predicting HLA-B27 expression" @default.
• W4387059637 cites W1986052810 @default.
• W4387059637 cites W2016184056 @default.
• W4387059637 cites W2030088199 @default.
• W4387059637 cites W2087088848 @default.
• W4387059637 cites W2123669024 @default.
• W4387059637 cites W2135067598 @default.
• W4387059637 cites W2543421865 @default.
• W4387059637 cites W2568455178 @default.
• W4387059637 cites W2802565218 @default.
• W4387059637 cites W2886522935 @default.
• W4387059637 cites W2895101137 @default.
• W4387059637 cites W2976240910 @default.
• W4387059637 cites W2982392732 @default.
• W4387059637 cites W3007929160 @default.
• W4387059637 cites W3014340804 @default.
• W4387059637 cites W3015791746 @default.
• W4387059637 cites W3024853795 @default.
• W4387059637 cites W3027102646 @default.
• W4387059637 cites W3036367715 @default.
• W4387059637 cites W3087947231 @default.
• W4387059637 cites W3119905018 @default.
• W4387059637 cites W3135278199 @default.
• W4387059637 cites W3144747894 @default.
• W4387059637 cites W3156165154 @default.
• W4387059637 cites W3168573813 @default.
• W4387059637 cites W3200133923 @default.
• W4387059637 cites W3206243497 @default.
• W4387059637 cites W3209060067 @default.
• W4387059637 cites W3213294096 @default.
• W4387059637 cites W3214744487 @default.
• W4387059637 cites W4200047015 @default.
• W4387059637 cites W4200103267 @default.
• W4387059637 cites W4205453886 @default.
• W4387059637 cites W4221132753 @default.
• W4387059637 cites W4229020811 @default.
• W4387059637 cites W4230650832 @default.
• W4387059637 cites W4234016370 @default.
• W4387059637 cites W4256193252 @default.
• W4387059637 cites W4280640234 @default.
• W4387059637 cites W4290038963 @default.
• W4387059637 doi "https://doi.org/10.1186/s12865-023-00566-z" @default.
• W4387059637 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37752439" @default.
• W4387059637 hasPublicationYear "2023" @default.
• W4387059637 type Work @default.
• W4387059637 citedByCount "0" @default.
• W4387059637 crossrefType "journal-article" @default.
• W4387059637 hasAuthorship W4387059637A5000080255 @default.
• W4387059637 hasAuthorship W4387059637A5006833753 @default.
• W4387059637 hasAuthorship W4387059637A5012777958 @default.
• W4387059637 hasAuthorship W4387059637A5015255981 @default.
• W4387059637 hasAuthorship W4387059637A5019560977 @default.
• W4387059637 hasAuthorship W4387059637A5021294207 @default.
• W4387059637 hasAuthorship W4387059637A5021585653 @default.
• W4387059637 hasAuthorship W4387059637A5023403656 @default.
• W4387059637 hasAuthorship W4387059637A5030972493 @default.
• W4387059637 hasAuthorship W4387059637A5045551132 @default.
• W4387059637 hasAuthorship W4387059637A5053911985 @default.
• W4387059637 hasAuthorship W4387059637A5056428506 @default.
• W4387059637 hasAuthorship W4387059637A5058544003 @default.
• W4387059637 hasAuthorship W4387059637A5072719400 @default.
• W4387059637 hasAuthorship W4387059637A5086856805 @default.
• W4387059637 hasBestOaLocation W43870596371 @default.
• W4387059637 hasConcept C126322002 @default.
• W4387059637 hasConcept C147483822 @default.
• W4387059637 hasConcept C188280979 @default.
• W4387059637 hasConcept C203014093 @default.
• W4387059637 hasConcept C2777402515 @default.
• W4387059637 hasConcept C2778091532 @default.
• W4387059637 hasConcept C34626388 @default.
• W4387059637 hasConcept C58471807 @default.
• W4387059637 hasConcept C71924100 @default.
• W4387059637 hasConcept C72563966 @default.
• W4387059637 hasConceptScore W4387059637C126322002 @default.
• W4387059637 hasConceptScore W4387059637C147483822 @default.
• W4387059637 hasConceptScore W4387059637C188280979 @default.
• W4387059637 hasConceptScore W4387059637C203014093 @default.
• W4387059637 hasConceptScore W4387059637C2777402515 @default.
• W4387059637 hasConceptScore W4387059637C2778091532 @default.
• W4387059637 hasConceptScore W4387059637C34626388 @default.
• W4387059637 hasConceptScore W4387059637C58471807 @default.

• next