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- W4387061917 abstract "Resting systolic blood pressure (SBP) is a primary determinant of left ventricular mass normalized to body surface area (LVM/BSA). The SBP response to stressors is augmented in many pathologies, and is thought to further influence LVM/BSA. Therefore, the increase in SBP due to muscle contraction may be associated with LVM/BSA. PURPOSE: Determine if a direct correlation exists between the SBP response to resistance exercise (eSBP) and LVM/BSA in healthy women. METHODS: Exercise consisted of 5 sets of bilateral leg extension at 70% of 1 repetition maximum with 60s rest intervals while continuously monitoring blood pressure by finger plethysmography. LVM was estimated using linear echocardiographic measurements from the parasternal long axis view. Pearson correlations were used to examine relationships of interest to the eSBP change from rest to the final 10s of each set. One-way ANOVA examined eSBP across sets. Data shown as mean ± SD. RESULTS: Twenty-six young, adult women participated (age 24 ± 4 yrs, height 165 ± 7 cm, body mass 64.4 ± 11.4 kg). Resting SBP (110 ± 9 mmHg, r = 0.496, p = 0.010), but not diastolic blood pressure (72 ± 8 mmHg, r = 0.203, p = 0.320) or heart rate (67 ± 12BPM, r = -0.318, p = 0.112) was shown to be directly correlated to LVM/BSA (72.7 ± 15.4 g/m2). Conversely, eSBP increased across sets (ANOVA p < 0.001) and was inversely related to LVM/BSA with a strengthening of the association across sets (set 1: 19.0 ± 12.8∆mmHg, r = -0.301, p = 0.134; set 2: 25.2 ± 12.3∆mmHg, r = -0.494, p = 0.010; set 3: 30.0 ± 11.6∆mmHg, r = -0.681, p = 0.001; set 4: 32.1 ± 13.7∆mmHg, r = -0.626, p = 0.001; set 5: 34.8 ± 14.9∆mmHg, r = -0.607, p = 0.001). Set 5 eSBP displayed a significant inverse trend vs interventricular septum width during diastole (0.90 ± 0.14 cm, r = -0.416, p = 0.034). Set 5 eSBP did not correlate to posterior wall thickness during diastole (0.89 ± 0.17 cm, r = -0.263, p = 0.193), or left ventricle internal diameter during diastole (4.30 ± 0.40 cm, r = -0.303, p = 0.131). CONCLUSION: This preliminary analysis confirms prior research showing greater resting systolic blood pressure is associated with greater left ventricular mass. Counter to the hypothesis, the current data suggests an inverse association between the further increase in systolic blood pressure during resistance exercise and left ventricular muscle mass in healthy young women." @default.
- W4387061917 created "2023-09-27" @default.
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- W4387061917 date "2023-09-01" @default.
- W4387061917 modified "2023-09-27" @default.
- W4387061917 title "Systolic Blood Pressure Response To Resistance Exercise Is Inversely Related To Left Ventricular Mass" @default.
- W4387061917 doi "https://doi.org/10.1249/01.mss.0000981580.32964.03" @default.
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