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- W4387077350 abstract "Type III receptor tyrosine kinase, e.g., PDGFR, are associated with various autoimmune diseases. To show the status of PDGFR and c-KIT targets, we performed the US patent analysis. The present study showed that the R&D of c-KIT target was much earlier than the R&D of PDGFR targets. Currently, the PDGFR-based target demonstrates more applications in the development of biological therapy. Our findings indicated that some inhibitors of c-KIT target contained sulfur elements or 1,3-diazine rings. The c-KIT target has more competitive edges for chemical drug discovery than the PDGFR target. c-KIT and PDGFR targets are currently preferable for drug discovery in autoimmune diseases. This study was the first to show R&D differentiation between PDGFR and c-KIT targets in drug development." @default.
- W4387077350 created "2023-09-28" @default.
- W4387077350 creator A5005784498 @default.
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- W4387077350 date "2023-09-27" @default.
- W4387077350 modified "2023-09-28" @default.
- W4387077350 title "Patent landscape of platelet growth factor receptor and c-KIT targets" @default.
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- W4387077350 doi "https://doi.org/10.4155/ppa-2023-0005" @default.
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