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- W4387082114 abstract "This systematic review and network meta-analysis aims to preliminarily investigate the efficacy of different orthodontic appliances for the treatment of pediatric obstructive sleep apnea (OSA). Electronic databases were systematically searched. Randomized and non-randomized controlled trials with patients <18 y treated with either mandibular advancement appliance (MAA), rapid maxillary expansion (RME), or myofunctional therapy (MFT) were included. A network meta-analysis using multivariate random effects was conducted to estimate pooled differences using the apnea-hypopnea index (AHI) as the main outcome. Eleven studies (595 patients) were included in the analysis. Compared with control, MAA was associated with significant reductions in AHI of −2.18/h (95%CI -3.48 to −0.89, p = 0.001). Combined treatment of RME + adenotonsillectomy (AT) and RME + MAA showed a significant decrease in AHI, with −5.13/h (95%CI -7.50 to −2.76, p < 0.0001) and −3.79 (95%CI -5.21 to −2.37, p < 0.0001), respectively. MFT was associated with a −2.45/h (95%CI -4.76 to −0.14, p = 0.038) decrease in AHI. However, RME alone was not associated with significant AHI reduction (0.02, 95%CI -1.72 to 1.75, p = 0.985). The heterogeneity of the network meta-analysis was I2 = 32.6%. Limited evidence indicated that MAA (alone or combined with RME) and RME + AT were associated with benefits for pediatric patients with OSA. This study could not find convincing evidence of a significant benefit of other orthodontic appliances over control." @default.
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- W4387082114 date "2023-12-01" @default.
- W4387082114 modified "2023-10-13" @default.
- W4387082114 title "Orthodontic appliances for the treatment of pediatric obstructive sleep apnea: A systematic review and network meta-analysis" @default.
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- W4387082114 doi "https://doi.org/10.1016/j.smrv.2023.101855" @default.
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