Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387095041> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4387095041 abstract "Abstract Background: Heavy metals may play an important role in hypertension. The aim of this study was to investigate the relationship between hypertension and exposure to manganese (Mn), lead (Pb), copper (Cu), zinc (Zn), cadmium (Cd) and antimony (Sb). Methods: A cross-sectional study of 3,446 subjects was conducted. Logistic regression was used to estimate the relationship between each metal exposure and risk of hypertension. The potential heterogeneity of groups according to sex, age and smoking status was investigated, and metal mixtures and interactions were assessed by Bayesian kernel machine regression (BKMR). Results: The logistic regression analysis identified Cu ([OR]=7.796, 95% [CI]: 3.395-17.903, P <0.001) and Cd (OR=1.894, 95% CI: 1.385-2.592, P <0.001) as risk factors for hypertension. The BKMR analysis indicated that all heavy metals had a complex, nonlinear exposure-response relationship with the risk of hypertension in participants aged 60-99; the stratified analysis of all Cu levels also showed a complex nonlinear relationship. The stratified analysis revealed a significant correlation between the plasma levels of heavy metals and risk of hypertension aged 30-59, nonsmokers, and women. We did not observe any interaction between the hypertensive status of study participants and exposure to the metals, but the logistic regression model revealed possible interactions; we provide explanations for these results. Conclusion: Plasma Cu and Cd levels were positively correlated with risk of hypertension when the metal levels were assessed individually or in combination and may be risk factors for hypertension. Future cohort studies with larger sample sizes and longer follow-up periods are necessary to confirm these associations." @default.
- W4387095041 created "2023-09-28" @default.
- W4387095041 creator A5037371045 @default.
- W4387095041 date "2023-09-27" @default.
- W4387095041 modified "2023-09-28" @default.
- W4387095041 title "Exposure to multiple heavy metals is associated with hypertension: A cross-sectional study in China" @default.
- W4387095041 cites W1998632119 @default.
- W4387095041 cites W2008453452 @default.
- W4387095041 cites W2008650611 @default.
- W4387095041 cites W2014968400 @default.
- W4387095041 cites W2064345922 @default.
- W4387095041 cites W2075162381 @default.
- W4387095041 cites W2080485883 @default.
- W4387095041 cites W2337170020 @default.
- W4387095041 cites W2395417791 @default.
- W4387095041 cites W2586125437 @default.
- W4387095041 cites W2596273064 @default.
- W4387095041 cites W2790505908 @default.
- W4387095041 cites W2913705661 @default.
- W4387095041 cites W2936965529 @default.
- W4387095041 cites W2952698708 @default.
- W4387095041 cites W2980817202 @default.
- W4387095041 cites W2990520434 @default.
- W4387095041 cites W2990801176 @default.
- W4387095041 cites W3031424135 @default.
- W4387095041 cites W3100709359 @default.
- W4387095041 cites W3108918126 @default.
- W4387095041 cites W3124685240 @default.
- W4387095041 cites W3193823764 @default.
- W4387095041 cites W3197338413 @default.
- W4387095041 cites W4233388177 @default.
- W4387095041 doi "https://doi.org/10.21203/rs.3.rs-3388025/v1" @default.
- W4387095041 hasPublicationYear "2023" @default.
- W4387095041 type Work @default.
- W4387095041 citedByCount "0" @default.
- W4387095041 crossrefType "posted-content" @default.
- W4387095041 hasAuthorship W4387095041A5037371045 @default.
- W4387095041 hasBestOaLocation W43870950411 @default.
- W4387095041 hasConcept C107872376 @default.
- W4387095041 hasConcept C126322002 @default.
- W4387095041 hasConcept C142052008 @default.
- W4387095041 hasConcept C142724271 @default.
- W4387095041 hasConcept C151956035 @default.
- W4387095041 hasConcept C185592680 @default.
- W4387095041 hasConcept C191897082 @default.
- W4387095041 hasConcept C192562407 @default.
- W4387095041 hasConcept C2776053758 @default.
- W4387095041 hasConcept C544657597 @default.
- W4387095041 hasConcept C71924100 @default.
- W4387095041 hasConceptScore W4387095041C107872376 @default.
- W4387095041 hasConceptScore W4387095041C126322002 @default.
- W4387095041 hasConceptScore W4387095041C142052008 @default.
- W4387095041 hasConceptScore W4387095041C142724271 @default.
- W4387095041 hasConceptScore W4387095041C151956035 @default.
- W4387095041 hasConceptScore W4387095041C185592680 @default.
- W4387095041 hasConceptScore W4387095041C191897082 @default.
- W4387095041 hasConceptScore W4387095041C192562407 @default.
- W4387095041 hasConceptScore W4387095041C2776053758 @default.
- W4387095041 hasConceptScore W4387095041C544657597 @default.
- W4387095041 hasConceptScore W4387095041C71924100 @default.
- W4387095041 hasFunder F4320321001 @default.
- W4387095041 hasLocation W43870950411 @default.
- W4387095041 hasOpenAccess W4387095041 @default.
- W4387095041 hasPrimaryLocation W43870950411 @default.
- W4387095041 hasRelatedWork W2071135625 @default.
- W4387095041 hasRelatedWork W2071766524 @default.
- W4387095041 hasRelatedWork W2277908348 @default.
- W4387095041 hasRelatedWork W2352296903 @default.
- W4387095041 hasRelatedWork W2377482533 @default.
- W4387095041 hasRelatedWork W2389709268 @default.
- W4387095041 hasRelatedWork W2606877433 @default.
- W4387095041 hasRelatedWork W3155604685 @default.
- W4387095041 hasRelatedWork W4211185036 @default.
- W4387095041 hasRelatedWork W4367460031 @default.
- W4387095041 isParatext "false" @default.
- W4387095041 isRetracted "false" @default.
- W4387095041 workType "article" @default.