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- W4387096543 abstract "Objective: VV ECMO is a standard therapy for patients with respiratory failure who have failed conventional therapy. Careful evaluation is necessary to determine candidacy due to limited resources. Few studies have examined outcomes of patients evaluated for VV ECMO, but rejected for cannulation. The objective of this study was to examine outcomes of patients rejected for VV ECMO cannulation. Methods: We conducted a retrospective review of patients evaluated but rejected for VV ECMO cannulation at a tertiary academic medical center between January 2020 and March 2023. Demographics, PMH, acute characteristics, and outcomes were collected. Results: 112 patients were identified. Patients were divided into two groups: those who survived and those who expired. There was no difference in ARDS therapies pre-ECMO evaluation. There was no difference in PaO2/FiO2 ratio. Overall 61.26% (95% CI: 52%, 70%) died. Those rejected due to improvement with medical management had lowest mortality, 39.7% (95% CI: 27.7%, 52.6%). Patients rejected due to multi-organ failure had higher mortality, 81.5% (95% CI: 63.6%, 92.9%). Other reasons for rejection with associated mortality were: age (83.3%), concerning neurological status (100%), prolonged mechanical ventilation (73.7%), chronic organ failure (76.2%), obesity (62.5%). Conclusions: Patients with severe ARDS rejected for ECMO cannulation due to improvement with medical management have a high survival rate. Patients with severe ARDS and contra-indications to ECMO have a high mortality if not offered ECMO support. It is unknown if mortality would differ if VV ECMO was offered. Research investigating ideal candidates for VV ECMO should be pursued." @default.
- W4387096543 created "2023-09-28" @default.
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- W4387096543 date "2023-09-01" @default.
- W4387096543 modified "2023-09-28" @default.
- W4387096543 title "146: Retrospective Analysis of Patients with ARDS deemed Not Candidates for VV ECMO Support" @default.
- W4387096543 doi "https://doi.org/10.1097/01.mat.0000990760.87869.dc" @default.
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