Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387103487> ?p ?o ?g. }
- W4387103487 abstract "Abstract Background Nonsteroidal anti-inflammatory drugs (NSAIDs) used for osteoarthritis (OA) in primary care may cause gastrointestinal or renal injury. This study estimated adherence to two quality indicators (QIs) to optimize NSAID safety: add proton pump inhibitors (PPI) to NSAIDs for patients with gastrointestinal (GI) risk (QI #1 NSAID-PPI) and avoid oral NSAIDs in chronic kidney disease (CKD) stage G4 or G5 (QI #2 NSAID-CKD). Methods This retrospective study included index primary care clinic visits for knee OA at our health system in 2019. The validation cohort consisted of a random sample of 60 patients. The remainder were included in the expanded cohort. Analysis of structured data extracts was validated against chart review of clinic visit notes (validation cohort) and estimated QI adherence (expanded cohort). Results Among 60 patients in the validation cohort, analysis of data extracts was validated against chart review for QI #1 NSAID-PPI (100% sensitivity and 91% specificity) and QI #2 NSAID-CKD (100% accuracy). Among 335 patients in the expanded cohort, 44% used NSAIDs, 27% used PPIs, 73% had elevated GI risk, and only 2% had CKD stage 4 or 5. Twenty-one percent used NSAIDs and had elevated GI risk but were not using PPIs. Therefore, adherence to QI #1 NSAID-PPI was 79% (95% CI, 74–83%). No patients with CKD stage 4 or 5 used NSAIDs. Therefore, adherence to QI #2 NSAID-CKD was 100%. Conclusion A substantial proportion of knee OA patients with GI risk factors did not receive PPI with NSAID therapy during primary care visits." @default.
- W4387103487 created "2023-09-28" @default.
- W4387103487 creator A5004685139 @default.
- W4387103487 creator A5008568063 @default.
- W4387103487 creator A5009928848 @default.
- W4387103487 creator A5012925369 @default.
- W4387103487 creator A5028086379 @default.
- W4387103487 creator A5032710721 @default.
- W4387103487 creator A5051004642 @default.
- W4387103487 creator A5055802359 @default.
- W4387103487 creator A5060700845 @default.
- W4387103487 creator A5082059665 @default.
- W4387103487 date "2023-09-27" @default.
- W4387103487 modified "2023-10-05" @default.
- W4387103487 title "Specification, validation, and adherence of quality indicators to optimize the safe use of nonsteroidal anti-inflammatory drugs for knee osteoarthritis pain in the primary care setting" @default.
- W4387103487 cites W1947261881 @default.
- W4387103487 cites W1970024336 @default.
- W4387103487 cites W1990824360 @default.
- W4387103487 cites W2036491373 @default.
- W4387103487 cites W2044515527 @default.
- W4387103487 cites W2093274439 @default.
- W4387103487 cites W2110922423 @default.
- W4387103487 cites W2117429908 @default.
- W4387103487 cites W2133278537 @default.
- W4387103487 cites W2144345791 @default.
- W4387103487 cites W2145218953 @default.
- W4387103487 cites W2153729660 @default.
- W4387103487 cites W2155965977 @default.
- W4387103487 cites W2164287243 @default.
- W4387103487 cites W2188931165 @default.
- W4387103487 cites W2322290949 @default.
- W4387103487 cites W2521602796 @default.
- W4387103487 cites W2607031541 @default.
- W4387103487 cites W2741315312 @default.
- W4387103487 cites W2886415937 @default.
- W4387103487 cites W2943119591 @default.
- W4387103487 cites W2955666772 @default.
- W4387103487 cites W2976141615 @default.
- W4387103487 cites W3000165474 @default.
- W4387103487 cites W3004142553 @default.
- W4387103487 cites W3087917567 @default.
- W4387103487 cites W4382681178 @default.
- W4387103487 doi "https://doi.org/10.1186/s12891-023-06904-x" @default.
- W4387103487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37759196" @default.
- W4387103487 hasPublicationYear "2023" @default.
- W4387103487 type Work @default.
- W4387103487 citedByCount "0" @default.
- W4387103487 crossrefType "journal-article" @default.
- W4387103487 hasAuthorship W4387103487A5004685139 @default.
- W4387103487 hasAuthorship W4387103487A5008568063 @default.
- W4387103487 hasAuthorship W4387103487A5009928848 @default.
- W4387103487 hasAuthorship W4387103487A5012925369 @default.
- W4387103487 hasAuthorship W4387103487A5028086379 @default.
- W4387103487 hasAuthorship W4387103487A5032710721 @default.
- W4387103487 hasAuthorship W4387103487A5051004642 @default.
- W4387103487 hasAuthorship W4387103487A5055802359 @default.
- W4387103487 hasAuthorship W4387103487A5060700845 @default.
- W4387103487 hasAuthorship W4387103487A5082059665 @default.
- W4387103487 hasBestOaLocation W43871034871 @default.
- W4387103487 hasConcept C126322002 @default.
- W4387103487 hasConcept C142724271 @default.
- W4387103487 hasConcept C167135981 @default.
- W4387103487 hasConcept C1862650 @default.
- W4387103487 hasConcept C198451711 @default.
- W4387103487 hasConcept C201903717 @default.
- W4387103487 hasConcept C204787440 @default.
- W4387103487 hasConcept C2776164576 @default.
- W4387103487 hasConcept C2778653478 @default.
- W4387103487 hasConcept C71924100 @default.
- W4387103487 hasConcept C72563966 @default.
- W4387103487 hasConceptScore W4387103487C126322002 @default.
- W4387103487 hasConceptScore W4387103487C142724271 @default.
- W4387103487 hasConceptScore W4387103487C167135981 @default.
- W4387103487 hasConceptScore W4387103487C1862650 @default.
- W4387103487 hasConceptScore W4387103487C198451711 @default.
- W4387103487 hasConceptScore W4387103487C201903717 @default.
- W4387103487 hasConceptScore W4387103487C204787440 @default.
- W4387103487 hasConceptScore W4387103487C2776164576 @default.
- W4387103487 hasConceptScore W4387103487C2778653478 @default.
- W4387103487 hasConceptScore W4387103487C71924100 @default.
- W4387103487 hasConceptScore W4387103487C72563966 @default.
- W4387103487 hasFunder F4320307765 @default.
- W4387103487 hasIssue "1" @default.
- W4387103487 hasLocation W43871034871 @default.
- W4387103487 hasLocation W43871034872 @default.
- W4387103487 hasOpenAccess W4387103487 @default.
- W4387103487 hasPrimaryLocation W43871034871 @default.
- W4387103487 hasRelatedWork W1971557041 @default.
- W4387103487 hasRelatedWork W2005712411 @default.
- W4387103487 hasRelatedWork W2081380988 @default.
- W4387103487 hasRelatedWork W2138481135 @default.
- W4387103487 hasRelatedWork W2157077459 @default.
- W4387103487 hasRelatedWork W2754539770 @default.
- W4387103487 hasRelatedWork W2937211356 @default.
- W4387103487 hasRelatedWork W2943558117 @default.
- W4387103487 hasRelatedWork W4308686283 @default.
- W4387103487 hasRelatedWork W4312780918 @default.
- W4387103487 hasVolume "24" @default.
- W4387103487 isParatext "false" @default.
- W4387103487 isRetracted "false" @default.