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• W4387104523 abstract "The coronavirus disease 2019 (COVID-19) pandemic has evolved to dynamic waves of different SARS-CoV-2 variants. Initially, children diagnosed with COVID-19 presented pulmonary involvement characterized by mild diseases. In the later waves of the COVID-19 pandemic, life-threatening non-pulmonary inflammatory diseases such as (1) aseptic meningoencephalitis (ME), (2) acute necrotizing encephalopathies (ANE), and (3) multisystem inflammatory syndrome in children (MIS-C) have been reported, affecting the pediatric population. To alert timely identification and prevention of the life-threatening non-pulmonary COVID-19, we present the cases of ME, ANE, and MIS-C in terms of clinical manifestation, cytokine profile, and follow-up consequences. Based on the immunopathogenesis and risk factors associated with non-pulmonary COVID-19, we delineate strategies for an early diagnosis and treatment to reduce morbidity and mortality in children." @default.
• W4387104523 created "2023-09-28" @default.
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• W4387104523 date "2023-09-26" @default.
• W4387104523 modified "2023-10-14" @default.
• W4387104523 title "Case report: Presentations and cytokine profiles of inflammatory non-pulmonary COVID-19 and related diseases in children" @default.
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• W4387104523 doi "https://doi.org/10.3389/fped.2023.1209772" @default.
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