Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387107046> ?p ?o ?g. }
- W4387107046 endingPage "10" @default.
- W4387107046 startingPage "1" @default.
- W4387107046 abstract "Since the first outbreak of coronavirus disease (COVID-19), many infected people have developed a severe infection, which is usually a sequel of cytokine overproduction. The chemokine receptor, such as chemokine receptor 5, also denoted as (CCR5) has a role in the pathogenicity of COVID-19 disease. The ongoing research paper tried to assess the impact role of CCR5Δ32 mutation in a group of Iraq SARS-CoV-2 infected patients. A total of 180 samples were enrolled in this study; 120 were patients infected with COVID-19 and verified by reverse transcriptase polymerase chain reaction (RT-PCR) in nasopharyngeal swabs. Those patients were categorized into two groups based on the severity of the disease: severe COVID-19, which included 60 patients and mild/moderate COVID-19 with 60 patients. Furthermore, 60 subjects confirmed to be COVID-19-negative were enrolled in this study as a control group. The nucleic DNA was obtained from whole blood, and the CCR5Δ32 mutation was genotyped and detected by polymerase chain reaction using specific primer sequences. Results of the current study mentioned that out of the 180 samples in this study, 100 (100%) were wild type for the CCR5 gene (CCR5-wt), while none (0%) were mutant type for the CCR5-Δ32. This research has demonstrated that none of the study patients have the mutant CCR5 gene type (CCR5-32), assuming a lack of the role of CCR5Δ32 in the prognosis of COVID-19 infection. Keywords: Chemokine receptor 5 (CCR5), CCR5Δ32 mutation, COVID-19, SARS-CoV-2." @default.
- W4387107046 created "2023-09-28" @default.
- W4387107046 creator A5001920308 @default.
- W4387107046 creator A5065610805 @default.
- W4387107046 creator A5092955354 @default.
- W4387107046 date "2023-09-15" @default.
- W4387107046 modified "2023-09-28" @default.
- W4387107046 title "The clinical impact of chemokine receptor CCR5 Δ32 mutation in SARS-CoV-2 infected patients" @default.
- W4387107046 cites W2009543813 @default.
- W4387107046 cites W2030491441 @default.
- W4387107046 cites W2038048329 @default.
- W4387107046 cites W2043842774 @default.
- W4387107046 cites W2113469729 @default.
- W4387107046 cites W2159514674 @default.
- W4387107046 cites W2983010058 @default.
- W4387107046 cites W3002865378 @default.
- W4387107046 cites W3009992310 @default.
- W4387107046 cites W3013498230 @default.
- W4387107046 cites W3014833803 @default.
- W4387107046 cites W3019181748 @default.
- W4387107046 cites W3019316721 @default.
- W4387107046 cites W3020512604 @default.
- W4387107046 cites W3020893626 @default.
- W4387107046 cites W3022531685 @default.
- W4387107046 cites W3023767473 @default.
- W4387107046 cites W3028729845 @default.
- W4387107046 cites W3029292308 @default.
- W4387107046 cites W3041879287 @default.
- W4387107046 cites W3092136311 @default.
- W4387107046 cites W3118265060 @default.
- W4387107046 cites W3129522222 @default.
- W4387107046 cites W3137011383 @default.
- W4387107046 cites W4206489430 @default.
- W4387107046 cites W4210567477 @default.
- W4387107046 cites W4214598775 @default.
- W4387107046 cites W4250559414 @default.
- W4387107046 cites W4281856483 @default.
- W4387107046 cites W4285110409 @default.
- W4387107046 doi "https://doi.org/10.21931/rb/2023.08.03.78" @default.
- W4387107046 hasPublicationYear "2023" @default.
- W4387107046 type Work @default.
- W4387107046 citedByCount "0" @default.
- W4387107046 crossrefType "journal-article" @default.
- W4387107046 hasAuthorship W4387107046A5001920308 @default.
- W4387107046 hasAuthorship W4387107046A5065610805 @default.
- W4387107046 hasAuthorship W4387107046A5092955354 @default.
- W4387107046 hasBestOaLocation W43871070461 @default.
- W4387107046 hasConcept C104317684 @default.
- W4387107046 hasConcept C126322002 @default.
- W4387107046 hasConcept C12823836 @default.
- W4387107046 hasConcept C13373296 @default.
- W4387107046 hasConcept C156719811 @default.
- W4387107046 hasConcept C157431215 @default.
- W4387107046 hasConcept C159047783 @default.
- W4387107046 hasConcept C170493617 @default.
- W4387107046 hasConcept C178790620 @default.
- W4387107046 hasConcept C185592680 @default.
- W4387107046 hasConcept C203014093 @default.
- W4387107046 hasConcept C2522874641 @default.
- W4387107046 hasConcept C2777563447 @default.
- W4387107046 hasConcept C2777648638 @default.
- W4387107046 hasConcept C2779134260 @default.
- W4387107046 hasConcept C3008058167 @default.
- W4387107046 hasConcept C49105822 @default.
- W4387107046 hasConcept C501734568 @default.
- W4387107046 hasConcept C524204448 @default.
- W4387107046 hasConcept C54355233 @default.
- W4387107046 hasConcept C71924100 @default.
- W4387107046 hasConcept C86803240 @default.
- W4387107046 hasConceptScore W4387107046C104317684 @default.
- W4387107046 hasConceptScore W4387107046C126322002 @default.
- W4387107046 hasConceptScore W4387107046C12823836 @default.
- W4387107046 hasConceptScore W4387107046C13373296 @default.
- W4387107046 hasConceptScore W4387107046C156719811 @default.
- W4387107046 hasConceptScore W4387107046C157431215 @default.
- W4387107046 hasConceptScore W4387107046C159047783 @default.
- W4387107046 hasConceptScore W4387107046C170493617 @default.
- W4387107046 hasConceptScore W4387107046C178790620 @default.
- W4387107046 hasConceptScore W4387107046C185592680 @default.
- W4387107046 hasConceptScore W4387107046C203014093 @default.
- W4387107046 hasConceptScore W4387107046C2522874641 @default.
- W4387107046 hasConceptScore W4387107046C2777563447 @default.
- W4387107046 hasConceptScore W4387107046C2777648638 @default.
- W4387107046 hasConceptScore W4387107046C2779134260 @default.
- W4387107046 hasConceptScore W4387107046C3008058167 @default.
- W4387107046 hasConceptScore W4387107046C49105822 @default.
- W4387107046 hasConceptScore W4387107046C501734568 @default.
- W4387107046 hasConceptScore W4387107046C524204448 @default.
- W4387107046 hasConceptScore W4387107046C54355233 @default.
- W4387107046 hasConceptScore W4387107046C71924100 @default.
- W4387107046 hasConceptScore W4387107046C86803240 @default.
- W4387107046 hasIssue "3" @default.
- W4387107046 hasLocation W43871070461 @default.
- W4387107046 hasOpenAccess W4387107046 @default.
- W4387107046 hasPrimaryLocation W43871070461 @default.
- W4387107046 hasRelatedWork W2019810109 @default.
- W4387107046 hasRelatedWork W2041590401 @default.
- W4387107046 hasRelatedWork W2053464542 @default.