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- W4387134830 abstract "<h3>Introduction/Background</h3> The purpose of this study is to develope a scoring system for predicting recurrence in early-stage adenocarcinoma of cervix after radical hysterectomy. <h3>Methodology</h3> The medical records of 322 patients with stage IA2-IIB cervical cancer with adenocarcinoma who underwent radical hysterectomy were retrospectively reviewed. <h3>Results</h3> There were 44 (13.7%) recurrences during the 57.6 months of median follow up period. The clinico-pathologic characteristics were analyzed with the univariate Cox proportional hazard method. Bootstrap resampling was performed 1,000 times for factors which showed statistical significance in this analysis. Histologic type, lymph node metastasis (LNM), parametrial invasion, and lympho-vascular space invasion showed bootstrap higher than 500 and these factors were included in multivariate analysis and incorporated to build a scoring system. This model showed better accuracy in terms of concordance (C) index in predicting recurrence than FIGO stage, adjusted FIGO stage, LNM, and risk group (0.817 vs 0.541, 0.778, 0.738, and 0.778; respectively). The calibration plot for recurrence also showed good calibration. <h3>Conclusion</h3> We have developed a robust scoring system that can provide accurate prediction of the recurrence in patients with adenocarcinoma of cervix. <h3>Disclosures</h3> none" @default.
- W4387134830 created "2023-09-29" @default.
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- W4387134830 date "2023-09-01" @default.
- W4387134830 modified "2023-10-18" @default.
- W4387134830 title "#408 Scoring system for predicting 3 and 5-year recurrence in early-stage adenocarcinoma of cervix after radical hysterectomy" @default.
- W4387134830 doi "https://doi.org/10.1136/ijgc-2023-esgo.140" @default.
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