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- W4387135037 abstract "<h3>Introduction/Background</h3> Ovarian Granulosa Cell Tumors have a particular clinical and evolutionary profile. Preoperative diagnosis is difficult. The aim of our study is to understand the diagnostic features of these tumors and to evaluate the therapeutic modalities. <h3>Methodology</h3> This is a retrospective study about eleven patients operated for ovarian granulosa cell tumors, collected during the period from January 1, 2016 to January 31, 2023. <h3>Results</h3> In this study, seven women had the adult-type Granulosa Cell Tumor of the Ovary (AGCT). The rest of the patients had Juvenile Granulosa Cell Tumor (JGCT) of ovary. The mean age of patients varied between 19 and 61 years. For the AGCT group, the mean age was 53 years. Four women were postmenopausal. Pelvic pain was the most common discovery circumstance. All tumors were unilateral. Their average size was 13 cm. Three patients had endometrial thickening. All women had optimal surgical treatment and none of them required adjuvant therapy. Regarding the JGCT group, the average age was 26 years. The masses were unilateral in all cases with a mean size of 13 cm. Only one patient had the tumor at the stage IC according to the International Federation of Obstetrician Gynecologists (FIGO). Unilateral adnexectomy, infracolic omentectomy and multiple peritoneal biopsies were performed. Furthermore, she required adjuvant chemotherapy after fertility preservation. The rest of the tumors were classified as stage IA according to FIGO. <h3>Conclusion</h3> Surgical staging and assessment of the risk of recurrence can optimize the management of Ovarian Granulosa Cell Tumors. Prospective randomized studies evaluating the efficacy of other therapeutic strategies are essential. <h3>Disclosures</h3> The authors have no conflicts of interest to declare. All co-authors have seen and agree with the contents of the manuscript and there is no financial interest to report." @default.
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- W4387135037 date "2023-09-01" @default.
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- W4387135037 title "#1013 Ovarian granulosa cell tumor: diagnostic and therapeutic challenges" @default.
- W4387135037 doi "https://doi.org/10.1136/ijgc-2023-esgo.689" @default.
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