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- W4387135539 abstract "<h3>Introduction/Background</h3> Sentinel lymph node (SLN) mapping with indocyanine green (ICG) with Mini-Invasive surgery (MIS) is becoming the standard technique in the treatment of early-stage endometrial cancer (ESEC). The setting up of a standardized surgical and pathology protocol to acquire proficiency is crucial to optimize the SLN detection rate. We sought to describe the first 18 months’ results of such implementation in a large metropolitan hospital in Milan. <h3>Methodology</h3> All patients diagnosed with ESEC, treated with MIS as primary surgery, and undergoing ICG injection to detect SLN, between 09/2021–03/2022, were included. Ultra staging technique for nodal analysis has been adopted. We assessed variables affecting successful and unsuccessful mapping. <h3>Results</h3> Of 46 included patients 80.4% had successful SLN mapping, with 54.3% bilateral and 26.1% monolateral detection. The overall rate of positive SLN was 6.5%, with 2 macro metastasis and 1 isolated tumor cells. Sites of SLN mapping were external iliac (64.4%), obturator fossa (20.3%), common iliac (10.2%). Considering three semesters time-frame, successful mapping progressively increased with (9/12)75.0%, (13/17)76.5%, (15/17)88.2% in the 1st, 2nd and 3rd semester, respectively. SLN empty nodes rates were 16%, 6%, 5% respectively. To gain such proficiency, we progressively adopted a composite standardized protocol including: injection-to-mapping time extension (8.3%, 20.0%, 29.4% respectively), cervical reinjection (0, 1, 1 case respectively), SLN frozen section in not obvious nodal tissue (0, 1, 4 cases respectively). Comparing successful and unsuccessful mapping cases, patients’ and tumor features did not significantly differ between the groups in the three time-frames. <h3>Conclusion</h3> Patients and tumor features did not affect the successful migration rate in ESEC SLN mapping in this initial period. On the other hand, a satisfactory rate of successful migration was reached after acquiring an adequate technical skill armamentarium, with a learning curve of about 30 cases. <h3>Disclosures</h3> no disclosures reported" @default.
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- W4387135539 date "2023-09-01" @default.
- W4387135539 modified "2023-10-18" @default.
- W4387135539 title "#158 Clinical pitfalls in setting up A ‘endometrial cancer sentinel lymph node mapping’ surgical protocol" @default.
- W4387135539 doi "https://doi.org/10.1136/ijgc-2023-esgo.281" @default.
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