Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387157046> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4387157046 abstract "To evaluate whether subcategorization of perineural invasion (PNI) improves the prognostic resolution of the American Joint Committee on Cancer, Eighth Edition (AJCC8) staging system in oral cavity squamous cell carcinoma (OCSCC).OCSCC tumor specimens from patients seen at a tertiary care institution who underwent primary surgical resection between January 2019 and June 2021 were sorted into four PNI categories: negative, intratumoral, peripheral, and extratumoral. The prognostic effect of these PNI categories were assessed through Kaplan-Meier, Cox regression, and log-rank testing using recurrence-free survival (RFS) and overall survival (OS) as primary and secondary outcomes respectively.A total of 158 patients were examined. The median follow-up time was 21 months. PNI subcategorization further stratified RFS (p = 0.007) and OS (p = 0.002). Extratumoral PNI was associated with a 4.5-fold increase in recurrence risk (adjusted hazards ratio [aHR]: 4.53; 95% confidence interval [CI]: 1.1-18.66) and worse OS when compared with PNI negative disease (aHR: 5.71; 95% CI: 1.0-32.67). Peripheral PNI was associated with worse OS (aHR: 5.7; 95% CI: 1.35-24.08) but not worse RFS (p = 0.18) when compared with PNI negative disease. Interestingly, intratumoral PNI was not associated with significant differences in RFS (p = 0.087) or OS (p = 0.22) when compared with PNI negative disease.Subcategorization of OCSCC tumors into extratumoral, peripheral, and intratumoral PNI stratifies RFS and OS when compared with patients with PNI negative disease in an incremental fashion. This pilot study suggests that there may be added benefit in subcategorization of PNI in the prognostic evaluation of OCSCC.IV Laryngoscope, 2023." @default.
- W4387157046 created "2023-09-30" @default.
- W4387157046 creator A5006446731 @default.
- W4387157046 creator A5016041746 @default.
- W4387157046 creator A5020195906 @default.
- W4387157046 creator A5027166662 @default.
- W4387157046 creator A5028189327 @default.
- W4387157046 date "2023-09-29" @default.
- W4387157046 modified "2023-09-30" @default.
- W4387157046 title "Subcategorization of Perineural Invasion Stratifies Oral Cavity Squamous Cell Carcinoma Prognosis" @default.
- W4387157046 cites W1532654778 @default.
- W4387157046 cites W1968359118 @default.
- W4387157046 cites W1996936425 @default.
- W4387157046 cites W2015515099 @default.
- W4387157046 cites W2062831861 @default.
- W4387157046 cites W2078159813 @default.
- W4387157046 cites W2113078044 @default.
- W4387157046 cites W2124809808 @default.
- W4387157046 cites W2136537082 @default.
- W4387157046 cites W2139725663 @default.
- W4387157046 cites W2261744332 @default.
- W4387157046 cites W2411455792 @default.
- W4387157046 cites W2461131482 @default.
- W4387157046 cites W2486277325 @default.
- W4387157046 cites W2939142318 @default.
- W4387157046 cites W2951988944 @default.
- W4387157046 cites W2960787469 @default.
- W4387157046 cites W2969238958 @default.
- W4387157046 cites W3011725410 @default.
- W4387157046 cites W3194476581 @default.
- W4387157046 cites W4226162565 @default.
- W4387157046 cites W4280512327 @default.
- W4387157046 doi "https://doi.org/10.1002/lary.31059" @default.
- W4387157046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37772957" @default.
- W4387157046 hasPublicationYear "2023" @default.
- W4387157046 type Work @default.
- W4387157046 citedByCount "0" @default.
- W4387157046 crossrefType "journal-article" @default.
- W4387157046 hasAuthorship W4387157046A5006446731 @default.
- W4387157046 hasAuthorship W4387157046A5016041746 @default.
- W4387157046 hasAuthorship W4387157046A5020195906 @default.
- W4387157046 hasAuthorship W4387157046A5027166662 @default.
- W4387157046 hasAuthorship W4387157046A5028189327 @default.
- W4387157046 hasConcept C121608353 @default.
- W4387157046 hasConcept C126322002 @default.
- W4387157046 hasConcept C143998085 @default.
- W4387157046 hasConcept C154945302 @default.
- W4387157046 hasConcept C2776397901 @default.
- W4387157046 hasConcept C2777154038 @default.
- W4387157046 hasConcept C2777546739 @default.
- W4387157046 hasConcept C3019992690 @default.
- W4387157046 hasConcept C41008148 @default.
- W4387157046 hasConcept C44249647 @default.
- W4387157046 hasConcept C50382708 @default.
- W4387157046 hasConcept C70845037 @default.
- W4387157046 hasConcept C71924100 @default.
- W4387157046 hasConcept C90924648 @default.
- W4387157046 hasConceptScore W4387157046C121608353 @default.
- W4387157046 hasConceptScore W4387157046C126322002 @default.
- W4387157046 hasConceptScore W4387157046C143998085 @default.
- W4387157046 hasConceptScore W4387157046C154945302 @default.
- W4387157046 hasConceptScore W4387157046C2776397901 @default.
- W4387157046 hasConceptScore W4387157046C2777154038 @default.
- W4387157046 hasConceptScore W4387157046C2777546739 @default.
- W4387157046 hasConceptScore W4387157046C3019992690 @default.
- W4387157046 hasConceptScore W4387157046C41008148 @default.
- W4387157046 hasConceptScore W4387157046C44249647 @default.
- W4387157046 hasConceptScore W4387157046C50382708 @default.
- W4387157046 hasConceptScore W4387157046C70845037 @default.
- W4387157046 hasConceptScore W4387157046C71924100 @default.
- W4387157046 hasConceptScore W4387157046C90924648 @default.
- W4387157046 hasLocation W43871570461 @default.
- W4387157046 hasLocation W43871570462 @default.
- W4387157046 hasOpenAccess W4387157046 @default.
- W4387157046 hasPrimaryLocation W43871570461 @default.
- W4387157046 hasRelatedWork W2014435840 @default.
- W4387157046 hasRelatedWork W2092701849 @default.
- W4387157046 hasRelatedWork W2104184505 @default.
- W4387157046 hasRelatedWork W2112392530 @default.
- W4387157046 hasRelatedWork W2528949658 @default.
- W4387157046 hasRelatedWork W3011259429 @default.
- W4387157046 hasRelatedWork W3089170113 @default.
- W4387157046 hasRelatedWork W3189544283 @default.
- W4387157046 hasRelatedWork W4230673599 @default.
- W4387157046 hasRelatedWork W4387157046 @default.
- W4387157046 isParatext "false" @default.
- W4387157046 isRetracted "false" @default.
- W4387157046 workType "article" @default.