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- W4387157435 abstract "Biomolecular condensates are dynamic structures formed through diverse mechanism, including liquid-liquid phase separation. These condensates have emerged as crucial regulators of cellular processes in eukaryotic cells, enabling the compartmentalization of specific biological reactions while allowing for dynamic exchange of molecules with the surrounding environment. RNA silencing, a conserved gene regulatory mechanism mediated by small RNAs (sRNAs), plays pivotal roles in various biological processes. Multiple types of biomolecular condensate, including dicing bodies, processing bodies, siRNA bodies, and Cajal bodies, have been identified as key players in RNA silencing pathways. These biomolecular condensates provide spatial compartmentation for the biogenesis, loading, action, and turnover of sRNAs. Moreover, they actively respond to stresses, such as viral infections, and modulate RNA silencing activities during stress responses. This review summarizes recent advances in understanding of dicing bodies and other biomolecular condensates involved in RNA silencing. We explore their formation, roles in RNA silencing, and contributions to antiviral resistance responses. This comprehensive overview provides insights into the functional significance of biomolecular condensates in RNA silencing and expands our understanding of their roles in gene expression and stress responses in plants." @default.
- W4387157435 created "2023-09-30" @default.
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- W4387157435 date "2023-09-29" @default.
- W4387157435 modified "2023-09-30" @default.
- W4387157435 title "Biomolecular condensates in plant RNA silencing: insights into formation, function, and stress responses" @default.
- W4387157435 doi "https://doi.org/10.1093/plcell/koad254" @default.
- W4387157435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37772963" @default.
- W4387157435 hasPublicationYear "2023" @default.
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