Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387159711> ?p ?o ?g. }
Showing items 1 to 48 of
48
with 100 items per page.
- W4387159711 abstract "The blood-brain barrier (BBB) is a dynamic physiological structure composed of microvascular endothelial cells, astrocytes, and pericytes. By coordinating the interaction between restricted transit of harmful substances, nutrient absorption, and metabolite clearance in the brain, the BBB is essential in preserving central nervous system homeostasis. Building in vitro models of the BBB is a valuable tool for exploring the pathophysiology of neurological disorders and creating pharmacological treatments. This study describes a procedure for creating an in vitro monolayer BBB cell model by seeding bEnd.3 cells into the upper chamber of a 24-well plate. To assess the integrity of cell barrier function, the conventional epithelial cell voltmeter was used to record the transmembrane electrical resistance of normal cells and CoCl2-induced hypoxic cells in real-time. We anticipate that the above experiments will provide effective ideas for the creation of in vitro models of BBB and drugs to treat disorders of central nervous system diseases." @default.
- W4387159711 created "2023-09-30" @default.
- W4387159711 date "2023-09-30" @default.
- W4387159711 modified "2023-09-30" @default.
- W4387159711 title "JoVE Video Dataset" @default.
- W4387159711 doi "https://doi.org/10.3791/65938-v" @default.
- W4387159711 hasPublicationYear "2023" @default.
- W4387159711 type Work @default.
- W4387159711 citedByCount "0" @default.
- W4387159711 crossrefType "journal-article" @default.
- W4387159711 hasConcept C1491633281 @default.
- W4387159711 hasConcept C169760540 @default.
- W4387159711 hasConcept C170493617 @default.
- W4387159711 hasConcept C185592680 @default.
- W4387159711 hasConcept C202751555 @default.
- W4387159711 hasConcept C24530287 @default.
- W4387159711 hasConcept C2778402981 @default.
- W4387159711 hasConcept C529278444 @default.
- W4387159711 hasConcept C55493867 @default.
- W4387159711 hasConcept C86803240 @default.
- W4387159711 hasConcept C95444343 @default.
- W4387159711 hasConceptScore W4387159711C1491633281 @default.
- W4387159711 hasConceptScore W4387159711C169760540 @default.
- W4387159711 hasConceptScore W4387159711C170493617 @default.
- W4387159711 hasConceptScore W4387159711C185592680 @default.
- W4387159711 hasConceptScore W4387159711C202751555 @default.
- W4387159711 hasConceptScore W4387159711C24530287 @default.
- W4387159711 hasConceptScore W4387159711C2778402981 @default.
- W4387159711 hasConceptScore W4387159711C529278444 @default.
- W4387159711 hasConceptScore W4387159711C55493867 @default.
- W4387159711 hasConceptScore W4387159711C86803240 @default.
- W4387159711 hasConceptScore W4387159711C95444343 @default.
- W4387159711 hasLocation W43871597111 @default.
- W4387159711 hasOpenAccess W4387159711 @default.
- W4387159711 hasPrimaryLocation W43871597111 @default.
- W4387159711 hasRelatedWork W1968719211 @default.
- W4387159711 hasRelatedWork W1975454920 @default.
- W4387159711 hasRelatedWork W1979570000 @default.
- W4387159711 hasRelatedWork W1998741829 @default.
- W4387159711 hasRelatedWork W2009081910 @default.
- W4387159711 hasRelatedWork W2017952116 @default.
- W4387159711 hasRelatedWork W2085322430 @default.
- W4387159711 hasRelatedWork W2167739272 @default.
- W4387159711 hasRelatedWork W2391604340 @default.
- W4387159711 hasRelatedWork W48403003 @default.
- W4387159711 isParatext "false" @default.
- W4387159711 isRetracted "false" @default.
- W4387159711 workType "article" @default.