FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387162337> ?p ?o ?g. }

• W4387162337 abstract "Abstract Wrist actigraphy is a non-invasive technology to monitor activity over extended periods of time. Specific alterations in circadian patterns of activity have been described in several psychiatric disorders and are associated with symptom severity in major depressive disorder (MDD). The aim of this study was to investigate the correlations between activity patterns and the response to different MDD treatments. We used actigraphy recordings acquired for 3 independent clinical trials investigating the response to internet-delivered cognitive behavioral therapy (iCBT), escitalopram, or ketamine. We designed a feature extraction procedure applicable both to recordings spanning a single circadian cycle, and to average circadian profiles. First, we investigated the effects of MDD treatments independently from magnitude of response, and found that each treatment altered a specific subset of features. We next asked whether features of activity patterns before treatment correlate with the magnitude of response to MDD treatment, and whether the correlations are treatment-specific. We found distinct signatures in the correlations between longitudinal changes in individual features and the response to different treatments. Next, we trained linear regression ensembles to model the response to treatment using the patterns of activity during the depressive episode and ran in-depth analysis of coefficients to characterize the differences between treatments. We found that better response is associated with higher between-days variability for iCBT, and with lower between-days variability for ketamine, while lower within-day fragmentation was common to both treatments. Our data suggests that the analysis of circadian patterns of activity can potentially be used for predicting the response to different MDD treatments, however larger confirmatory studies are required for future clinical applications." @default.
• W4387162337 created "2023-09-30" @default.
• W4387162337 creator A5034336227 @default.
• W4387162337 creator A5036769741 @default.
• W4387162337 creator A5041913517 @default.
• W4387162337 creator A5046658044 @default.
• W4387162337 creator A5063179816 @default.
• W4387162337 creator A5082468471 @default.
• W4387162337 date "2023-09-29" @default.
• W4387162337 modified "2023-10-17" @default.
• W4387162337 title "Correlations between patterns of activity and the response to treatment yield distinct signatures for different antidepressant treatments" @default.
• W4387162337 cites W1989757811 @default.
• W4387162337 cites W1999142409 @default.
• W4387162337 cites W2017247763 @default.
• W4387162337 cites W2023081218 @default.
• W4387162337 cites W2045854014 @default.
• W4387162337 cites W2066821552 @default.
• W4387162337 cites W2114645041 @default.
• W4387162337 cites W2117180085 @default.
• W4387162337 cites W2123157432 @default.
• W4387162337 cites W2133649842 @default.
• W4387162337 cites W2141466449 @default.
• W4387162337 cites W2146409144 @default.
• W4387162337 cites W2171839813 @default.
• W4387162337 cites W2260776258 @default.
• W4387162337 cites W2286673660 @default.
• W4387162337 cites W2586691160 @default.
• W4387162337 cites W2599480332 @default.
• W4387162337 cites W2775282581 @default.
• W4387162337 cites W2797066666 @default.
• W4387162337 cites W2896681908 @default.
• W4387162337 cites W2900603166 @default.
• W4387162337 cites W2921561928 @default.
• W4387162337 cites W2936607937 @default.
• W4387162337 cites W2942204937 @default.
• W4387162337 cites W2947138402 @default.
• W4387162337 cites W2959446187 @default.
• W4387162337 cites W2982693253 @default.
• W4387162337 cites W3032575279 @default.
• W4387162337 cites W3034895811 @default.
• W4387162337 cites W3121610863 @default.
• W4387162337 cites W3153477612 @default.
• W4387162337 cites W3159379604 @default.
• W4387162337 cites W3161802057 @default.
• W4387162337 cites W3180628988 @default.
• W4387162337 cites W3215563353 @default.
• W4387162337 cites W3217489025 @default.
• W4387162337 cites W4200118999 @default.
• W4387162337 cites W4200535604 @default.
• W4387162337 cites W4200584800 @default.
• W4387162337 cites W4226197145 @default.
• W4387162337 cites W4229849994 @default.
• W4387162337 cites W4231169313 @default.
• W4387162337 cites W4247665917 @default.
• W4387162337 cites W4253305902 @default.
• W4387162337 cites W4282003914 @default.
• W4387162337 doi "https://doi.org/10.1101/2023.09.29.23294935" @default.
• W4387162337 hasPublicationYear "2023" @default.
• W4387162337 type Work @default.
• W4387162337 citedByCount "0" @default.
• W4387162337 crossrefType "posted-content" @default.
• W4387162337 hasAuthorship W4387162337A5034336227 @default.
• W4387162337 hasAuthorship W4387162337A5036769741 @default.
• W4387162337 hasAuthorship W4387162337A5041913517 @default.
• W4387162337 hasAuthorship W4387162337A5046658044 @default.
• W4387162337 hasAuthorship W4387162337A5063179816 @default.
• W4387162337 hasAuthorship W4387162337A5082468471 @default.
• W4387162337 hasBestOaLocation W43871623371 @default.
• W4387162337 hasConcept C121446783 @default.
• W4387162337 hasConcept C15744967 @default.
• W4387162337 hasConcept C169760540 @default.
• W4387162337 hasConcept C169900460 @default.
• W4387162337 hasConcept C2778996325 @default.
• W4387162337 hasConcept C2779177272 @default.
• W4387162337 hasConcept C2779583969 @default.
• W4387162337 hasConcept C2780051608 @default.
• W4387162337 hasConcept C2781161787 @default.
• W4387162337 hasConcept C70410870 @default.
• W4387162337 hasConcept C71924100 @default.
• W4387162337 hasConceptScore W4387162337C121446783 @default.
• W4387162337 hasConceptScore W4387162337C15744967 @default.
• W4387162337 hasConceptScore W4387162337C169760540 @default.
• W4387162337 hasConceptScore W4387162337C169900460 @default.
• W4387162337 hasConceptScore W4387162337C2778996325 @default.
• W4387162337 hasConceptScore W4387162337C2779177272 @default.
• W4387162337 hasConceptScore W4387162337C2779583969 @default.
• W4387162337 hasConceptScore W4387162337C2780051608 @default.
• W4387162337 hasConceptScore W4387162337C2781161787 @default.
• W4387162337 hasConceptScore W4387162337C70410870 @default.
• W4387162337 hasConceptScore W4387162337C71924100 @default.
• W4387162337 hasLocation W43871623371 @default.
• W4387162337 hasOpenAccess W4387162337 @default.
• W4387162337 hasPrimaryLocation W43871623371 @default.
• W4387162337 hasRelatedWork W1588650552 @default.
• W4387162337 hasRelatedWork W1892453938 @default.
• W4387162337 hasRelatedWork W2018640359 @default.
• W4387162337 hasRelatedWork W2069288238 @default.
• W4387162337 hasRelatedWork W2149240801 @default.
• W4387162337 hasRelatedWork W2522921805 @default.
• W4387162337 hasRelatedWork W2912922183 @default.

• next