FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387165164> ?p ?o ?g. }

• W4387165164 abstract "Abstract Host sex is an important source of heterogeneity in the severity of epidemics. Pinpointing the mechanisms causing this heterogeneity can be difficult because differences in behaviour among sexes (e.g. greater territorial aggression in males) can bias exposure risk, obfuscating the role of immune function, which can lead to differences in pathology, in driving differential susceptibility between sexes. Thus, sex-biased transmission driven by differences in immune function independent of behaviour is poorly understood, especially in non-mammalian systems. Here we examine the previously unexplored potential for male-biased pathology to affect transmission using an avian host-pathogen system. We employ a sex-dependent multistate transmission model parameterized with isolated, individual-based experimental exposures of domestic canaries and experimental transmission data of house finches. The experiment revealed that male birds have shorter incubation periods, longer recovery periods, higher pathogen burdens, and greater disease pathology, than females. Our model revealed that male-biased pathology led to epidemic size rapidly increasing with the proportion of male birds, with a nearly 16-fold increase in total epidemic size from an all-female to an all-male simulation. Our results demonstrate that female-biased resistance, independent of male behaviour, can drive sex-dependent transmission in wildlife, indicating that sex-based differences in immune function, not just differences in exposure risk, can shape epidemic dynamics." @default.
• W4387165164 created "2023-09-30" @default.
• W4387165164 creator A5020490463 @default.
• W4387165164 creator A5024651377 @default.
• W4387165164 creator A5055621313 @default.
• W4387165164 creator A5069220556 @default.
• W4387165164 creator A5092965805 @default.
• W4387165164 date "2023-09-29" @default.
• W4387165164 modified "2023-10-16" @default.
• W4387165164 title "Male pathology regardless of behaviour drives transmission in an avian host-pathogen system" @default.
• W4387165164 cites W1510515664 @default.
• W4387165164 cites W1969594466 @default.
• W4387165164 cites W1973799576 @default.
• W4387165164 cites W1977206198 @default.
• W4387165164 cites W1980631290 @default.
• W4387165164 cites W1987176045 @default.
• W4387165164 cites W1988798237 @default.
• W4387165164 cites W1989659247 @default.
• W4387165164 cites W1992366678 @default.
• W4387165164 cites W2008072444 @default.
• W4387165164 cites W2023671939 @default.
• W4387165164 cites W2036096221 @default.
• W4387165164 cites W2040029225 @default.
• W4387165164 cites W2050621940 @default.
• W4387165164 cites W2068176566 @default.
• W4387165164 cites W2068606060 @default.
• W4387165164 cites W2069251911 @default.
• W4387165164 cites W2076921587 @default.
• W4387165164 cites W2078694298 @default.
• W4387165164 cites W2102674923 @default.
• W4387165164 cites W2106912468 @default.
• W4387165164 cites W2119160928 @default.
• W4387165164 cites W2121905902 @default.
• W4387165164 cites W2124561604 @default.
• W4387165164 cites W2134483051 @default.
• W4387165164 cites W2139306902 @default.
• W4387165164 cites W2141844994 @default.
• W4387165164 cites W2144620185 @default.
• W4387165164 cites W2146828219 @default.
• W4387165164 cites W2150095215 @default.
• W4387165164 cites W2158077163 @default.
• W4387165164 cites W2158386957 @default.
• W4387165164 cites W2160511185 @default.
• W4387165164 cites W2160625753 @default.
• W4387165164 cites W2163106920 @default.
• W4387165164 cites W2203064303 @default.
• W4387165164 cites W2221972269 @default.
• W4387165164 cites W2326938199 @default.
• W4387165164 cites W2331512552 @default.
• W4387165164 cites W2346818067 @default.
• W4387165164 cites W2738826362 @default.
• W4387165164 cites W2740143262 @default.
• W4387165164 cites W2770582930 @default.
• W4387165164 cites W2790153087 @default.
• W4387165164 cites W2794108969 @default.
• W4387165164 cites W2895288138 @default.
• W4387165164 cites W3004434318 @default.
• W4387165164 cites W3016622466 @default.
• W4387165164 cites W3036635684 @default.
• W4387165164 cites W3112632811 @default.
• W4387165164 cites W3150478107 @default.
• W4387165164 cites W3171139551 @default.
• W4387165164 cites W3201741730 @default.
• W4387165164 cites W4241748149 @default.
• W4387165164 doi "https://doi.org/10.1101/2023.09.28.559954" @default.
• W4387165164 hasPublicationYear "2023" @default.
• W4387165164 type Work @default.
• W4387165164 citedByCount "0" @default.
• W4387165164 crossrefType "posted-content" @default.
• W4387165164 hasAuthorship W4387165164A5020490463 @default.
• W4387165164 hasAuthorship W4387165164A5024651377 @default.
• W4387165164 hasAuthorship W4387165164A5055621313 @default.
• W4387165164 hasAuthorship W4387165164A5069220556 @default.
• W4387165164 hasAuthorship W4387165164A5092965805 @default.
• W4387165164 hasBestOaLocation W43871651641 @default.
• W4387165164 hasConcept C119599485 @default.
• W4387165164 hasConcept C126831891 @default.
• W4387165164 hasConcept C127413603 @default.
• W4387165164 hasConcept C138496976 @default.
• W4387165164 hasConcept C142724271 @default.
• W4387165164 hasConcept C15744967 @default.
• W4387165164 hasConcept C159047783 @default.
• W4387165164 hasConcept C18903297 @default.
• W4387165164 hasConcept C203014093 @default.
• W4387165164 hasConcept C2776035688 @default.
• W4387165164 hasConcept C2776460866 @default.
• W4387165164 hasConcept C2779134260 @default.
• W4387165164 hasConcept C2779448149 @default.
• W4387165164 hasConcept C2992243407 @default.
• W4387165164 hasConcept C42407357 @default.
• W4387165164 hasConcept C46312422 @default.
• W4387165164 hasConcept C71924100 @default.
• W4387165164 hasConcept C761482 @default.
• W4387165164 hasConcept C86803240 @default.
• W4387165164 hasConcept C8891405 @default.
• W4387165164 hasConcept C90856448 @default.
• W4387165164 hasConceptScore W4387165164C119599485 @default.
• W4387165164 hasConceptScore W4387165164C126831891 @default.
• W4387165164 hasConceptScore W4387165164C127413603 @default.
• W4387165164 hasConceptScore W4387165164C138496976 @default.

• next