Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387169417> ?p ?o ?g. }
- W4387169417 abstract "Brain derived neurotrophic factor (BDNF) is one of the most extensively studied and widespread growth factors in the brain. BDNF and its receptors are the critical factors having multipotent impact on the central nervous system (CNS). The biological function of BDNF primarily mediated by two receptors, tropomyosin receptor kinase B (TrkB) receptor and p75 neurotrophin receptor. BDNF contributes a pivotal role in neuronal and glial development, modulation and maintaining overall synaptic plasticity of the brain; therefore, widely involved in psychiatric diseases. Current hypotheses indicates that abnormal BDNF level, a vital condition for psychiatric and neurodegeneration diseases are mainly due to the disruption of the BDNF-associated signaling cascades. It is, therefore, crucial to understand how BDNF coordinate the psychiatric diseases in the brain. This review begins with the history of BDNF and its biology in brain homeostasis and focuses on several aspects of BDNF signaling. In addition, the review addresses the impact of BDNF level in diverse neuropsychiatric disorders including major depressive disorder, schizophrenia, bipolar disorder, post-traumatic stress disorder and, possible biological mechanisms of BDNF that may shed new insight for future therapeutic use and drug development." @default.
- W4387169417 created "2023-09-30" @default.
- W4387169417 creator A5022083217 @default.
- W4387169417 creator A5073642710 @default.
- W4387169417 date "2023-09-21" @default.
- W4387169417 modified "2023-09-30" @default.
- W4387169417 title "The Role of Brain-Derived Neurotrophic Factor in Psychiatric Disorders" @default.
- W4387169417 cites W144423133 @default.
- W4387169417 cites W1495527708 @default.
- W4387169417 cites W1519555255 @default.
- W4387169417 cites W1527035699 @default.
- W4387169417 cites W1593725384 @default.
- W4387169417 cites W1830398839 @default.
- W4387169417 cites W1843473465 @default.
- W4387169417 cites W1964670163 @default.
- W4387169417 cites W1965831320 @default.
- W4387169417 cites W1967017538 @default.
- W4387169417 cites W1969349734 @default.
- W4387169417 cites W1973652904 @default.
- W4387169417 cites W1973883693 @default.
- W4387169417 cites W1974119296 @default.
- W4387169417 cites W1975707733 @default.
- W4387169417 cites W1976551375 @default.
- W4387169417 cites W1978586367 @default.
- W4387169417 cites W1982889157 @default.
- W4387169417 cites W1984603208 @default.
- W4387169417 cites W1985260834 @default.
- W4387169417 cites W1986244535 @default.
- W4387169417 cites W1986977063 @default.
- W4387169417 cites W1987309900 @default.
- W4387169417 cites W1987920581 @default.
- W4387169417 cites W1987968465 @default.
- W4387169417 cites W1990548736 @default.
- W4387169417 cites W1991049734 @default.
- W4387169417 cites W1994958608 @default.
- W4387169417 cites W1996314032 @default.
- W4387169417 cites W1996375332 @default.
- W4387169417 cites W1996706750 @default.
- W4387169417 cites W1996893328 @default.
- W4387169417 cites W1999972660 @default.
- W4387169417 cites W2002844435 @default.
- W4387169417 cites W2002918346 @default.
- W4387169417 cites W2003665687 @default.
- W4387169417 cites W2008267423 @default.
- W4387169417 cites W2009208338 @default.
- W4387169417 cites W2015445474 @default.
- W4387169417 cites W2016763472 @default.
- W4387169417 cites W2017320329 @default.
- W4387169417 cites W2018734015 @default.
- W4387169417 cites W2020626300 @default.
- W4387169417 cites W2022196959 @default.
- W4387169417 cites W2022823367 @default.
- W4387169417 cites W2026538105 @default.
- W4387169417 cites W2027304084 @default.
- W4387169417 cites W2030433930 @default.
- W4387169417 cites W2030776582 @default.
- W4387169417 cites W2033367566 @default.
- W4387169417 cites W2034209442 @default.
- W4387169417 cites W2035172439 @default.
- W4387169417 cites W2037335353 @default.
- W4387169417 cites W2037383099 @default.
- W4387169417 cites W2038122755 @default.
- W4387169417 cites W2039302083 @default.
- W4387169417 cites W2049672215 @default.
- W4387169417 cites W2050042714 @default.
- W4387169417 cites W2051721448 @default.
- W4387169417 cites W2054491289 @default.
- W4387169417 cites W2055018912 @default.
- W4387169417 cites W2057170051 @default.
- W4387169417 cites W205881385 @default.
- W4387169417 cites W2059819643 @default.
- W4387169417 cites W2061169091 @default.
- W4387169417 cites W2067155791 @default.
- W4387169417 cites W2067302534 @default.
- W4387169417 cites W2073611916 @default.
- W4387169417 cites W2074918990 @default.
- W4387169417 cites W2076764860 @default.
- W4387169417 cites W2078316783 @default.
- W4387169417 cites W2082739481 @default.
- W4387169417 cites W2083047064 @default.
- W4387169417 cites W2084434253 @default.
- W4387169417 cites W2084899195 @default.
- W4387169417 cites W2086317124 @default.
- W4387169417 cites W2086755370 @default.
- W4387169417 cites W2086835104 @default.
- W4387169417 cites W2091376817 @default.
- W4387169417 cites W2092238952 @default.
- W4387169417 cites W2094073259 @default.
- W4387169417 cites W2096180958 @default.
- W4387169417 cites W2096264487 @default.
- W4387169417 cites W2107923630 @default.
- W4387169417 cites W2110696099 @default.
- W4387169417 cites W2110795584 @default.
- W4387169417 cites W2111038577 @default.
- W4387169417 cites W2115742198 @default.
- W4387169417 cites W2119493316 @default.
- W4387169417 cites W2120667767 @default.
- W4387169417 cites W2120832844 @default.
- W4387169417 cites W2121471393 @default.
- W4387169417 cites W2121651624 @default.