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- W4387172079 abstract "The formation of phase-separated condensates by many biomolecules is now widely accepted as the basic principle of membrane-less organelle (MLO) formation in the cell. However, various subcompartments form independently yet in parallel, which raises the question of how similar molecules can remain separated in different compartments but also join the same compartment when required. In this chapter, the assembly mechanism of the Cajal body, a classical but mysterious nuclear substructure, is discussed as an example. A characteristic pattern of charged patches in the intrinsically disordered regions (IDRs) of Cajal body components is highlighted as a key element explaining the behavior of biomolecule complexes involved in Cajal body formation." @default.
- W4387172079 created "2023-09-30" @default.
- W4387172079 creator A5011208145 @default.
- W4387172079 creator A5086803746 @default.
- W4387172079 date "2023-01-01" @default.
- W4387172079 modified "2023-09-30" @default.
- W4387172079 title "Winding and Tangling. An Initial Phase of Membrane-Less Organelle Formation" @default.
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- W4387172079 doi "https://doi.org/10.1007/978-981-99-4886-4_7" @default.
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