Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387184444> ?p ?o ?g. }
- W4387184444 abstract "Intracerebral hemorrhage (ICH) is a subtype of stroke with a high mortality rate. Oxidative stress cascades play an important role in brain injury after ICH. Cannabidiol, a major non-psychotropic phytocannabinoids, has drawn increasing interest in recent years as a potential therapeutic intervention for various neuropsychiatric disorders. Here we provide a comprehensive review of the potential therapeutic effects of cannabidiol in countering oxidative stress resulting from ICH. The review elaborates on the various sources of oxidative stress post-ICH, including mitochondrial dysfunction, excitotoxicity, iron toxicity, inflammation, and also highlights cannabidiol's ability to inhibit ROS/RNS generation from these sources. The article also delves into cannabidiol's role in promoting ROS/RNS scavenging through the Nrf2/ARE pathway, detailing both extranuclear and intranuclear regulatory mechanisms. Overall, the review underscores cannabidiol's promising antioxidant effects in the context of ICH and suggests its potential as a therapeutic option." @default.
- W4387184444 created "2023-09-30" @default.
- W4387184444 creator A5027961969 @default.
- W4387184444 creator A5031963674 @default.
- W4387184444 creator A5049384131 @default.
- W4387184444 creator A5049540619 @default.
- W4387184444 creator A5058560135 @default.
- W4387184444 creator A5059703639 @default.
- W4387184444 date "2023-09-28" @default.
- W4387184444 modified "2023-10-18" @default.
- W4387184444 title "Anti-oxidant effects of cannabidiol relevant to intracerebral hemorrhage" @default.
- W4387184444 cites W1176583637 @default.
- W4387184444 cites W1553366132 @default.
- W4387184444 cites W1566562478 @default.
- W4387184444 cites W1927188913 @default.
- W4387184444 cites W1964182457 @default.
- W4387184444 cites W1967236260 @default.
- W4387184444 cites W1977089823 @default.
- W4387184444 cites W1980686102 @default.
- W4387184444 cites W1982482955 @default.
- W4387184444 cites W1987936460 @default.
- W4387184444 cites W1991420366 @default.
- W4387184444 cites W2018617838 @default.
- W4387184444 cites W2021760273 @default.
- W4387184444 cites W2028323326 @default.
- W4387184444 cites W2028688399 @default.
- W4387184444 cites W2033122095 @default.
- W4387184444 cites W2038582574 @default.
- W4387184444 cites W2046136399 @default.
- W4387184444 cites W2051154935 @default.
- W4387184444 cites W2062991442 @default.
- W4387184444 cites W2076598575 @default.
- W4387184444 cites W2083004303 @default.
- W4387184444 cites W2083600673 @default.
- W4387184444 cites W2093507774 @default.
- W4387184444 cites W2096102502 @default.
- W4387184444 cites W2099595170 @default.
- W4387184444 cites W2101283650 @default.
- W4387184444 cites W2102354517 @default.
- W4387184444 cites W2113024198 @default.
- W4387184444 cites W2119898593 @default.
- W4387184444 cites W2132826785 @default.
- W4387184444 cites W2135443811 @default.
- W4387184444 cites W2140197131 @default.
- W4387184444 cites W2146142796 @default.
- W4387184444 cites W2146565954 @default.
- W4387184444 cites W2147049445 @default.
- W4387184444 cites W2158282742 @default.
- W4387184444 cites W2162356875 @default.
- W4387184444 cites W2165201727 @default.
- W4387184444 cites W2175833749 @default.
- W4387184444 cites W2214900079 @default.
- W4387184444 cites W2288552312 @default.
- W4387184444 cites W2460828608 @default.
- W4387184444 cites W2471605942 @default.
- W4387184444 cites W2542650944 @default.
- W4387184444 cites W2552770931 @default.
- W4387184444 cites W2561120791 @default.
- W4387184444 cites W2562322488 @default.
- W4387184444 cites W2565474450 @default.
- W4387184444 cites W2619122250 @default.
- W4387184444 cites W2625710117 @default.
- W4387184444 cites W2756343284 @default.
- W4387184444 cites W2786945379 @default.
- W4387184444 cites W2793512619 @default.
- W4387184444 cites W2798231473 @default.
- W4387184444 cites W2808620289 @default.
- W4387184444 cites W2888814179 @default.
- W4387184444 cites W2890803317 @default.
- W4387184444 cites W2898687486 @default.
- W4387184444 cites W2905264787 @default.
- W4387184444 cites W2910004036 @default.
- W4387184444 cites W2912062398 @default.
- W4387184444 cites W2914962560 @default.
- W4387184444 cites W2930559544 @default.
- W4387184444 cites W2936440883 @default.
- W4387184444 cites W2942802808 @default.
- W4387184444 cites W2943280814 @default.
- W4387184444 cites W2952687383 @default.
- W4387184444 cites W2965789561 @default.
- W4387184444 cites W2968164813 @default.
- W4387184444 cites W2971999469 @default.
- W4387184444 cites W2982171504 @default.
- W4387184444 cites W2995162523 @default.
- W4387184444 cites W3013855701 @default.
- W4387184444 cites W3015936268 @default.
- W4387184444 cites W3026586600 @default.
- W4387184444 cites W3083586210 @default.
- W4387184444 cites W3098640872 @default.
- W4387184444 cites W3110258185 @default.
- W4387184444 cites W3119914875 @default.
- W4387184444 cites W3131136542 @default.
- W4387184444 cites W3131445899 @default.
- W4387184444 cites W3133989845 @default.
- W4387184444 cites W3137991710 @default.
- W4387184444 cites W3164501445 @default.
- W4387184444 cites W3187669646 @default.
- W4387184444 cites W3195925936 @default.
- W4387184444 cites W3203982111 @default.
- W4387184444 cites W3207259270 @default.