Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387184879> ?p ?o ?g. }
- W4387184879 abstract "Introduction Sea cucumbers are cultivated mainly for their valuable body wall. Polybrominated diphenyl ethers are common persistent pollutants in sea waters with known impacts on aquatic animals nonetheless not yet studied for the body wall of sea cucumbers. Methods Using ltra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Triple-TOF-MS), we investigated the metabolic impact of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on the body wall of Apostichopus japonicus . etabolite changes and metabolic pathway alterations were assessed in response to three distinct concentrations of BDE-47: 0.1 µg/L, 1.0 µg/L, and 10.0 µg/L. REsults Exposure to BDE-47 led to notable alterations in the metabolic profiles of the body wall. A total of 95~102 metabolites in the 0.1 ~ 10.0 µg/L BDE-47 treated group were altered significantly, and various disrupted metabolic pathways were identified and characterized. These metabolites and metabolic pathways were mainly involved in lipid metabolism, energy metabolism, immunity, oxidative stress, inflammation, and neurotoxicity. Discussion The findings of our study shed light on the potential health risks that polybrominated diphenyl ethers present to sea cucumbers. This underscores the imperative for both researchers and policymakers to delve deeper into further investigations and studies. These results indicate the necessity for enhanced monitoring and management practices within the sea cucumber aquaculture industry to mitigate the impact of these persistent organic pollutants and protect the health and safety of this valuable resource." @default.
- W4387184879 created "2023-09-30" @default.
- W4387184879 creator A5003521550 @default.
- W4387184879 creator A5016731451 @default.
- W4387184879 creator A5025464801 @default.
- W4387184879 creator A5026349472 @default.
- W4387184879 creator A5040243318 @default.
- W4387184879 creator A5040694365 @default.
- W4387184879 creator A5055710591 @default.
- W4387184879 creator A5060951975 @default.
- W4387184879 date "2023-09-28" @default.
- W4387184879 modified "2023-09-30" @default.
- W4387184879 title "Metabolic profiling of Apostichopus japonicus body wall exposed to a typical type of PBDEs: potential health risks and impact on sea cucumber health" @default.
- W4387184879 cites W1502461125 @default.
- W4387184879 cites W1553665319 @default.
- W4387184879 cites W1592921716 @default.
- W4387184879 cites W1962867466 @default.
- W4387184879 cites W1966724263 @default.
- W4387184879 cites W1970294370 @default.
- W4387184879 cites W1973569766 @default.
- W4387184879 cites W1979273823 @default.
- W4387184879 cites W1981348969 @default.
- W4387184879 cites W1985258509 @default.
- W4387184879 cites W1986691777 @default.
- W4387184879 cites W1990456174 @default.
- W4387184879 cites W1991009266 @default.
- W4387184879 cites W1993849862 @default.
- W4387184879 cites W1994745985 @default.
- W4387184879 cites W1995702065 @default.
- W4387184879 cites W2003052366 @default.
- W4387184879 cites W2007220451 @default.
- W4387184879 cites W2008870304 @default.
- W4387184879 cites W2011023970 @default.
- W4387184879 cites W2014418676 @default.
- W4387184879 cites W2019005043 @default.
- W4387184879 cites W2019087671 @default.
- W4387184879 cites W2026432427 @default.
- W4387184879 cites W2030901818 @default.
- W4387184879 cites W2031731336 @default.
- W4387184879 cites W2033489975 @default.
- W4387184879 cites W2047266682 @default.
- W4387184879 cites W2057477349 @default.
- W4387184879 cites W2060039000 @default.
- W4387184879 cites W2070785261 @default.
- W4387184879 cites W2072385944 @default.
- W4387184879 cites W2076832110 @default.
- W4387184879 cites W2077077476 @default.
- W4387184879 cites W2081060350 @default.
- W4387184879 cites W2083869024 @default.
- W4387184879 cites W2086933999 @default.
- W4387184879 cites W2090543008 @default.
- W4387184879 cites W2103150508 @default.
- W4387184879 cites W2107919309 @default.
- W4387184879 cites W2110256992 @default.
- W4387184879 cites W2123954892 @default.
- W4387184879 cites W2125214333 @default.
- W4387184879 cites W2125872855 @default.
- W4387184879 cites W2132106503 @default.
- W4387184879 cites W2134841682 @default.
- W4387184879 cites W2137296676 @default.
- W4387184879 cites W2137815066 @default.
- W4387184879 cites W2151153377 @default.
- W4387184879 cites W2152737703 @default.
- W4387184879 cites W2165710337 @default.
- W4387184879 cites W2171448529 @default.
- W4387184879 cites W2227751224 @default.
- W4387184879 cites W2259857244 @default.
- W4387184879 cites W2288836413 @default.
- W4387184879 cites W2553406244 @default.
- W4387184879 cites W2586539752 @default.
- W4387184879 cites W2605068021 @default.
- W4387184879 cites W2795145094 @default.
- W4387184879 cites W2811420221 @default.
- W4387184879 cites W2884740025 @default.
- W4387184879 cites W2905626574 @default.
- W4387184879 cites W2962756593 @default.
- W4387184879 cites W2971799452 @default.
- W4387184879 cites W2974988625 @default.
- W4387184879 cites W2979783930 @default.
- W4387184879 cites W2985897872 @default.
- W4387184879 cites W2999982998 @default.
- W4387184879 cites W3015067867 @default.
- W4387184879 cites W3035688912 @default.
- W4387184879 cites W3035809029 @default.
- W4387184879 cites W3036304341 @default.
- W4387184879 cites W3044773400 @default.
- W4387184879 cites W3048376921 @default.
- W4387184879 cites W3106231446 @default.
- W4387184879 cites W3125029478 @default.
- W4387184879 cites W3132911139 @default.
- W4387184879 cites W3161181118 @default.
- W4387184879 cites W3164007252 @default.
- W4387184879 cites W3164440536 @default.
- W4387184879 cites W3197597446 @default.
- W4387184879 cites W3199045581 @default.
- W4387184879 cites W3202843024 @default.
- W4387184879 cites W4205775889 @default.
- W4387184879 cites W4205897825 @default.
- W4387184879 cites W4207022089 @default.
- W4387184879 cites W4220813692 @default.