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- W4387189708 abstract "Background: Preterm labor is the leading cause of perinatal morbidity & mortality and one of the leading causes of infant mortality. Despite substantial efforts to introduce new therapies for prevention of preterm labor, it continues to contribute signicantly to neonatal and infant mortality. Aim: To compare the efcacy of magnesium sulfate and nifedipine for tocolysis in preterm labor. Methods: This randomized clinical control study was conducted out at the department of Obstetrics & Gynaecology, S.N.M.C., Agra from Dec.2020 to Sept.2022. A total of 100 patients of preterm labor,>18 years of age with singleton pregnancy of gestational age between 28-33 weeks 6days were included in the study and selected on the basis of inclusion & exclusion criteria, and randomly divided into two groups (50 each) i.e. Group 1 (magnesium sulfate) & Group 2 (Nifedipine).Outcome variables like cessation of uterine contractions till 48 hours (efcacy) were noted for successful or unsuccessful outcome. Results: The mean gestational age in group1 was 31.66±1.80 weeks and in group2 was 31.72±1.68 weeks (p>0.05).There was cessation of uterine contractions in 44 (88%) and no cessation in 6 (12%) patients in Group 1 while in Group 2, it was seen in 35 (70%) and 15 (30%) patients respectively. So, efcacy was 88% in group 1(MgSO4) and 70% in group 2(oral nifedipine) with p-value of 0.0495. Conclusion: Magnesium sulfate has higher efcacy i.e. 88% for acute tocolysis in preterm labor as compared to oral nifedipine and can be used as rst line drug to treat preterm labor." @default.
- W4387189708 created "2023-09-30" @default.
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- W4387189708 date "2023-09-01" @default.
- W4387189708 modified "2023-09-30" @default.
- W4387189708 title "EFFICACY AND SAFETY OF MAGNESIUM SULFATE AND NIFEDIPINE FOR TOCOLYSIS IN PRETERM LABOR - A COMPARATIVE STUDY" @default.
- W4387189708 doi "https://doi.org/10.36106/ijsr/7806626" @default.
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