Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387203397> ?p ?o ?g. }
- W4387203397 endingPage "90" @default.
- W4387203397 startingPage "73" @default.
- W4387203397 abstract "Plant secondary metabolites, including alkaloids, are important sources of natural bioactive compounds with pharmaceutical and agricultural applications. The estimated number of plant-derived alkaloids is over 60% of all potential drugs. Alkaloids and their derivatives have a variety of biological activities, including antioxidants, antibacterial activity, antihyperglycemic activity, antiinflammatory activity, and anticancer activity. Moreover, several alkaloids are known as efficient drugs for different treatments, including chronic kidney, Alzheimer’s, and Parkinson's diseases, and antagonists (Santos et al., 2020). Although the extraction and purification of alkaloids are major sources of plant-derived drugs, the traditional method depends on the season and environmental factors. Besides that, chemical synthesis methods show poor yields and injure human health. Therefore, microbial alkaloids are a promising alternative for producing specialized drugs. This chapter covers the three approaches to producing alkaloids from microbes. Some well-known alkaloids are produced by endophytes, such as indole, isoindole, pyrrolidine, pyridone, and berberine alkaloids. Microbial transformation systems allow the production of target alkaloids in large quantities. In addition, the engineered E. coli and S. cerevisiae have rapidly developed the ability to produce alkaloids. This method has promising alternative strategies for using renewable carbon sources. Moreover, this chapter also presents the applications of alkaloids in the pharmaceutical and agricultural fields." @default.
- W4387203397 created "2023-09-30" @default.
- W4387203397 creator A5004094002 @default.
- W4387203397 creator A5070372134 @default.
- W4387203397 creator A5092972226 @default.
- W4387203397 date "2024-01-01" @default.
- W4387203397 modified "2023-10-14" @default.
- W4387203397 title "Microbial alkaloids and their pharmaceutical and agricultural application" @default.
- W4387203397 cites W125474061 @default.
- W4387203397 cites W1540714253 @default.
- W4387203397 cites W1952773426 @default.
- W4387203397 cites W1964151866 @default.
- W4387203397 cites W1990007616 @default.
- W4387203397 cites W1990127633 @default.
- W4387203397 cites W1993997409 @default.
- W4387203397 cites W1999537570 @default.
- W4387203397 cites W2010793133 @default.
- W4387203397 cites W2013226691 @default.
- W4387203397 cites W2018415677 @default.
- W4387203397 cites W2022547437 @default.
- W4387203397 cites W2042151209 @default.
- W4387203397 cites W2060557067 @default.
- W4387203397 cites W2066065652 @default.
- W4387203397 cites W2069573525 @default.
- W4387203397 cites W2120168903 @default.
- W4387203397 cites W2132316821 @default.
- W4387203397 cites W2195045928 @default.
- W4387203397 cites W2219292229 @default.
- W4387203397 cites W2238009938 @default.
- W4387203397 cites W2269292559 @default.
- W4387203397 cites W2316244444 @default.
- W4387203397 cites W2327180527 @default.
- W4387203397 cites W2328731288 @default.
- W4387203397 cites W2343408589 @default.
- W4387203397 cites W2404127947 @default.
- W4387203397 cites W2411417007 @default.
- W4387203397 cites W2472977484 @default.
- W4387203397 cites W2509419923 @default.
- W4387203397 cites W2525731773 @default.
- W4387203397 cites W2549330703 @default.
- W4387203397 cites W2589537368 @default.
- W4387203397 cites W2594351524 @default.
- W4387203397 cites W2607164284 @default.
- W4387203397 cites W2742067202 @default.
- W4387203397 cites W2753462628 @default.
- W4387203397 cites W2783076208 @default.
- W4387203397 cites W2791644413 @default.
- W4387203397 cites W2793782505 @default.
- W4387203397 cites W2795396508 @default.
- W4387203397 cites W2796883330 @default.
- W4387203397 cites W2797780713 @default.
- W4387203397 cites W2804625199 @default.
- W4387203397 cites W2805274902 @default.
- W4387203397 cites W2885416359 @default.
- W4387203397 cites W2889282585 @default.
- W4387203397 cites W2889573928 @default.
- W4387203397 cites W2895828174 @default.
- W4387203397 cites W2899753112 @default.
- W4387203397 cites W2901123564 @default.
- W4387203397 cites W2909599232 @default.
- W4387203397 cites W2909763373 @default.
- W4387203397 cites W2911549438 @default.
- W4387203397 cites W2911567382 @default.
- W4387203397 cites W2914241118 @default.
- W4387203397 cites W2914281490 @default.
- W4387203397 cites W2916167720 @default.
- W4387203397 cites W2916401536 @default.
- W4387203397 cites W2917911772 @default.
- W4387203397 cites W2946156466 @default.
- W4387203397 cites W2948168413 @default.
- W4387203397 cites W2949911621 @default.
- W4387203397 cites W2954918352 @default.
- W4387203397 cites W2955754230 @default.
- W4387203397 cites W2958189973 @default.
- W4387203397 cites W2963716412 @default.
- W4387203397 cites W2967350153 @default.
- W4387203397 cites W2969861558 @default.
- W4387203397 cites W2972058749 @default.
- W4387203397 cites W2980396502 @default.
- W4387203397 cites W2983340723 @default.
- W4387203397 cites W2983757964 @default.
- W4387203397 cites W2991949678 @default.
- W4387203397 cites W2993720587 @default.
- W4387203397 cites W3000376148 @default.
- W4387203397 cites W3000574072 @default.
- W4387203397 cites W3000680906 @default.
- W4387203397 cites W3003176227 @default.
- W4387203397 cites W3004834517 @default.
- W4387203397 cites W3005554050 @default.
- W4387203397 cites W3010397387 @default.
- W4387203397 cites W3011258307 @default.
- W4387203397 cites W3012132035 @default.
- W4387203397 cites W3012409679 @default.
- W4387203397 cites W3013214374 @default.
- W4387203397 cites W3022442709 @default.
- W4387203397 cites W3025398096 @default.
- W4387203397 cites W3028258796 @default.
- W4387203397 cites W3041804410 @default.