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- W4387203870 abstract "Xylooligosaccharides riched in xylobiose and xylotriose exhibit various biological activities as prebiotics. However, the prebiotics of xylooligosaccharides for regulating the intestinal microbiota in colitis models has been rarely investigated. In this study, differences in prebiotic ability of xylooligosaccharides samples from paper mulberry branches using different methods, including autohydrolysis (termed as 170AH), sequent purification by polystyrene-divinylbenzene copolymer resin (termed as 170AH-XAD), and enzymatic hydrolysis using endo-β-1,4-xylanase (170AH-XAD-E) were investigated. Results revealed that 170AH-XAD-E possessing higher fractions of xylobiose and xylotriose exhibited the best performance in vitro by promoting the proliferation of Bifidobacterium adolescentis and Lactobacillus acidophilus, with utilization rates of 92.30% and 91.00%, respectively. Additionally, 170AH-XAD-E outperformed the other samples in increasing the species' abundance of in vivo intestinal microbiota in colitis mouse model induced by Escherichia coli. Furthermore, 170AH-XAD-E selectively promoted the growth of Bacteroides, while inhibiting the proliferation of Firmicutes, Proteobacteria, and Actinobacteriota. These abilities of 170AH-XAD-E may be due to its potential to upregulate the population of intestinal microbiota associated with the functional abundance of Cell wall/membrane/envelope biogenesis and Inorganic ion transport and metabolism. Overall, this work demonstrates that XOS with high contents of xylobiose and xylotriose possesses excellent potential as intestinal microbiota regulators and anti-colitis agents." @default.
- W4387203870 created "2023-09-30" @default.
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- W4387203870 date "2023-12-01" @default.
- W4387203870 modified "2023-10-03" @default.
- W4387203870 title "Preparing xylooligosaccharides from paper mulberry branches as a promising prebiotic candidate for in vitro regulation of intestinal microbiota in colitis" @default.
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- W4387203870 doi "https://doi.org/10.1016/j.indcrop.2023.117521" @default.
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