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- W4387206263 abstract "Aging: A reinvigorating boost for the thymus A fusion of two signaling proteins temporarily reverses declining function in the ageing immune system. Early in life, an organ called the thymus plays a critical role in producing diverse T cell populations that can respond to a wide variety of threats. Thymus function decreases rapidly with age, but researchers led by Jacques Galipeau of Emory University in the USA may have uncovered a strategy for jump-starting the thymus later in life. They constructed a protein, ‘GIFT7’, which combines two immune-stimulating proteins, and discovered that it stimulated both thymus cell division and T cell production. GIFT7 treatment helped elderly mice mount a robust response against viral infection, with immune activity equivalent to much younger animals. Although the rejuvenation is not permanent, even transient stimulation might protect elderly patients undergoing bone marrow transplantation against infection." @default.
- W4387206263 created "2023-09-30" @default.
- W4387206263 date "2015-05-01" @default.
- W4387206263 modified "2023-09-30" @default.
- W4387206263 doi "https://doi.org/10.1002/cti2.2015.4.issue-5" @default.
- W4387206263 hasPublicationYear "2015" @default.
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